{"id":"W2594114810","doi":"10.1042/bcj20160832","title":"Binding and inhibition of the ternary complex factor Elk-4/Sap1 by the adapter protein Dok-4","year":2017,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Transactivation; Biology; Ternary complex; Cell biology; Pleckstrin homology domain; Signal transducing adaptor protein; Molecular biology; Binding site; GRB2; Signal transduction; Biochemistry; Transcription factor; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000708446,0.00008029238,0.00006769814,0.000007989582,0.0003168175,0.00007007057,0.0001901803,0.0000938183,0.00002929471],"category_scores_gemma":[0.00005057257,0.00004298261,0.00006726865,0.00001132383,0.0001849496,0.000005881225,0.0001444119,0.0001579885,0.000001134221],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007016683,"about_ca_system_score_gemma":0.00001382731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006465484,"about_ca_topic_score_gemma":0.000001060739,"domain_scores_codex":[0.9995169,0.00002737051,0.0001264553,0.0001105999,0.000113652,0.0001050233],"domain_scores_gemma":[0.9995023,0.000003362534,0.0001810972,0.0002338964,0.00003587031,0.00004349394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004737078,0.000009002566,0.001508396,0.000004426243,0.00001953522,5.226526e-7,0.0000152897,5.629911e-8,0.9894484,0.00001225739,0.007118009,0.001816734],"study_design_scores_gemma":[0.0003203853,0.00007209013,0.01532894,0.00002653557,0.00001090155,0.00009877743,0.00002606512,0.00000775831,0.9705876,0.0001152502,0.01333533,0.00007034603],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984026,0.000175496,0.00009033169,0.0008533184,0.0001111679,0.00008930553,0.00002227027,0.000001825252,0.0002536872],"genre_scores_gemma":[0.9991852,0.00002840262,0.0001309956,0.0001256343,0.0003244264,0.000001463585,0.000008010958,0.000008403028,0.0001874536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01886078,"threshold_uncertainty_score":0.2436736,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01484392801296382,"score_gpt":0.2363084070349562,"score_spread":0.2214644790219924,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}