{"id":"W2594128595","doi":"10.1038/543174a","title":"Show drugs work before selling them","year":2017,"lang":"en","type":"article","venue":"Nature","topic":"Pharmaceutical Economics and Policy","field":"Economics, Econometrics and Finance","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Work (physics); Business; Chemistry; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.004279464,0.0005029888,0.0008737819,0.0008510947,0.001695969,0.005886053,0.0007242541,0.006375497,0.07000924],"category_scores_gemma":[0.02677187,0.0003978183,0.0007121235,0.001379453,0.002904221,0.007204326,0.001276123,0.004185027,0.0132762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003748162,"about_ca_system_score_gemma":0.003893441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008946081,"about_ca_topic_score_gemma":0.01038095,"domain_scores_codex":[0.9959401,0.001557688,0.0001507318,0.0003704861,0.001506295,0.0004747357],"domain_scores_gemma":[0.9770553,0.01520659,0.00282845,0.001365767,0.002153449,0.001390444],"domain_codex":null,"domain_gemma":"evaluation","domain_candidate":"evaluation","domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001169385,0.0006812416,0.01632982,0.0009523851,0.0003193157,0.000331301,0.0005091317,0.003161429,0.003109456,0.5348665,0.2872158,0.1513542],"study_design_scores_gemma":[0.0003069929,0.0006131359,0.02910434,0.000476995,0.000305864,0.0003196909,0.001474115,0.003638864,0.006949008,0.3933348,0.5633612,0.0001151264],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"commentary","genre_scores_codex":[0.0783058,0.01935435,0.01096901,0.2552206,0.008130226,0.0002315263,0.00322321,0.0006599201,0.6239053],"genre_scores_gemma":[0.7372793,0.008572133,0.004144235,0.05064755,0.002901278,0.0001353828,0.000905137,0.0002674814,0.1951475],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.9957206,"threshold_uncertainty_score":0.2342042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05069420909240877,"score_gpt":0.2955117639835635,"score_spread":0.2448175548911548,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}