{"id":"W2594206110","doi":"10.1093/biolreprod/85.s1.767","title":"Understanding Oxidative Stress in Donor Fibroblasts for Enhancing Reprogramming Efficiency.","year":2011,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Animal Genetics and Reproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Guelph","funders":"","keywords":"Reprogramming; Cell biology; Biology; Oxidative stress; Senescence; Somatic cell; Reactive oxygen species; Somatic cell nuclear transfer; Mitochondrion; Stem cell; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005251762,0.0001140315,0.00014881,0.00009471789,0.00006486184,0.000003534415,0.00009039759,0.0001538496,0.000004981401],"category_scores_gemma":[0.0001875545,0.0001081761,0.00006691062,0.0001298439,0.0001606181,0.000005122353,0.00004960008,0.0000577826,7.858321e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002830586,"about_ca_system_score_gemma":0.00003576074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005696359,"about_ca_topic_score_gemma":0.0001329375,"domain_scores_codex":[0.9986869,0.00004926424,0.0002870949,0.0007275332,0.00004134113,0.0002078742],"domain_scores_gemma":[0.9993348,0.000008234079,0.0001848001,0.0003523413,0.00009484994,0.00002498986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002539825,0.0001148076,0.007716501,0.00004014696,0.00002774549,2.091542e-7,0.0003504065,0.0001126044,0.9855263,0.0004348728,0.00002408306,0.005398343],"study_design_scores_gemma":[0.0002849261,0.001093387,0.001827889,0.00002542329,0.00001010754,0.000009162854,0.0007442415,0.0000403036,0.9932705,0.000657724,0.001901335,0.000134978],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8938633,0.001135106,0.1040235,0.00003536251,0.0003447761,0.0003747317,0.000006171398,0.00001226758,0.0002048285],"genre_scores_gemma":[0.9912537,0.0001859306,0.00802192,0.000003476896,0.0002899817,0.00003354855,0.00005239691,0.00001370779,0.000145302],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09739044,"threshold_uncertainty_score":0.4411293,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07077174815420223,"score_gpt":0.2802675620473403,"score_spread":0.2094958138931381,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}