{"id":"W2594206110","doi":"10.1093/biolreprod/85.s1.767","title":"Understanding Oxidative Stress in Donor Fibroblasts for Enhancing Reprogramming Efficiency.","year":2011,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Animal Genetics and Reproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Guelph","funders":"","keywords":"Reprogramming; Cell biology; Biology; Oxidative stress; Senescence; Somatic cell; Reactive oxygen species; Somatic cell nuclear transfer; Mitochondrion; Stem cell; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000282902,0.0002986458,0.0001843578,0.0001884992,0.0001477986,0.0003557217,0.0002038108,0.0003192234,0.001256023],"category_scores_gemma":[0.0001708523,0.000118916,0.0002449144,0.0001873523,0.0001545755,0.000300165,0.0002139061,0.0005629138,0.0004120643],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002788646,"about_ca_system_score_gemma":0.0002283407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003578508,"about_ca_topic_score_gemma":0.0006911982,"domain_scores_codex":[0.999873,0.00001975259,0.000011237,0.00002701249,0.00005237323,0.00001665905],"domain_scores_gemma":[0.9999173,0.00001445019,0.00002682303,0.00001044716,0.0000197422,0.00001122668],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002051002,0.00001456436,0.0002191142,0.0001256802,0.000004022787,0.00004335302,0.00002054599,0.00006695381,0.9914243,0.0002373418,0.00006440537,0.007759057],"study_design_scores_gemma":[0.00001123261,0.0001727924,0.002541507,0.00002897662,0.00002755594,0.0004620408,0.00004794846,0.001021159,0.9832965,0.0003920415,0.01199076,0.000007550861],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7799833,0.05827353,0.1445447,0.00180723,0.00061352,0.0004657339,0.001467644,0.0005010171,0.01234324],"genre_scores_gemma":[0.925492,0.02208113,0.04566798,0.0004619756,0.00005702932,0.0002209519,0.0008396686,0.00005453387,0.005124664],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001256023,"threshold_uncertainty_score":0.004201829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07077174815420223,"score_gpt":0.2802675620473403,"score_spread":0.2094958138931381,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}