{"id":"W2594291948","doi":"10.1182/blood.v104.11.1223.1223","title":"Ferritin Heavy Chain, a Repressor of the Human β-Globin Gene That Binds a Conserved Cagtgc Motif, Is Bound to the Repressed β-Globin Promoter In Vivo in K562 Cells and Specifically Binds an Analogous Site in the Mouse βMajor-Globin Promoter.","year":2004,"lang":"en","type":"article","venue":"Blood","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Molecular biology; Biology; Globin; Chromatin immunoprecipitation; Promoter; Repressor; Chromatin; Locus control region; Binding site; Gene; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009784781,0.0002601202,0.0001578678,0.0001088211,0.0001376844,0.0002054601,0.0001322909,0.0001521934,0.001262347],"category_scores_gemma":[0.00006223485,0.000204034,0.0001871141,0.0001139422,0.0002012111,0.00008361675,0.000150246,0.0003669175,0.0007313584],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003136915,"about_ca_system_score_gemma":0.0001921494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00132931,"about_ca_topic_score_gemma":0.002133345,"domain_scores_codex":[0.9999144,0.000008301728,0.000006837899,0.00003430806,0.00001938217,0.00001671173],"domain_scores_gemma":[0.9999424,0.000009825707,0.00001791054,0.000007963036,0.000004576146,0.00001732914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001999737,0.000004469588,0.00008845283,0.000007844078,0.000001418036,0.00001100279,0.00000427302,0.000009241306,0.9995901,0.00002560579,0.00001543798,0.0002220529],"study_design_scores_gemma":[0.00001824273,0.00008450505,0.008587696,0.00000485252,0.000008530337,0.0002652025,0.00001522049,0.0008040676,0.9875894,0.00004749037,0.002571294,0.000003582377],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992092,0.001305625,0.004420373,0.00005950459,0.00002655896,0.0000205156,0.0006603543,0.0001025198,0.001312533],"genre_scores_gemma":[0.9897808,0.0005375245,0.00247871,0.00004553622,0.000007607588,0.00002473928,0.002419468,0.00003599818,0.004669758],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00132931,"threshold_uncertainty_score":0.004222929,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01871352511324793,"score_gpt":0.248172112602591,"score_spread":0.2294585874893431,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}