{"id":"W2594340397","doi":"10.1016/j.jinsphys.2017.03.001","title":"Population-associated heterogeneity of the digestive Cys protease complement in Colorado potato beetle, Leptinotarsa decemlineata","year":2017,"lang":"en","type":"article","venue":"Journal of Insect Physiology","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Centre Hospitalier Universitaire de Québec; Fonds de recherche du Québec – Nature et technologies; Université Laval; U.S. Department of Agriculture","keywords":"Colorado potato beetle; Biology; Leptinotarsa; Midgut; Protease; Cathepsin; Population; Cystatin; Cysteine protease; Cathepsin L; Proteases; Cathepsin B; Biochemistry; Botany; Enzyme; Larva; Cystatin C","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002709653,0.0001366146,0.0003200362,0.0000447296,0.000163376,0.00001339346,0.0005160235,0.0001273191,0.000007438572],"category_scores_gemma":[0.0003737837,0.0000989133,0.000182212,0.00005295147,0.0001489828,0.000007684226,0.0001773473,0.000173572,6.402122e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004361299,"about_ca_system_score_gemma":0.000142602,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002456942,"about_ca_topic_score_gemma":0.001409671,"domain_scores_codex":[0.9987955,0.0001936778,0.0004951815,0.0001574253,0.0001514293,0.0002068021],"domain_scores_gemma":[0.9982011,0.0000223193,0.001045649,0.0004314597,0.0002537118,0.00004571118],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004632972,0.0002049536,0.3254652,0.00001616883,0.000098326,0.00000622975,0.00005385694,0.0005090218,0.6727834,0.00002092954,0.0001771232,0.0002014623],"study_design_scores_gemma":[0.0009815677,0.0005605042,0.8750989,0.00004663905,0.00002123313,0.00001318753,0.00002350554,0.00002886609,0.1226595,0.0002829758,0.0001916741,0.00009144533],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991286,0.0002176797,0.00001661506,0.0001260187,0.0002033549,0.0002169438,0.00003930804,0.00000108359,0.00005038827],"genre_scores_gemma":[0.9993712,0.00008461854,0.0002050067,0.0001350788,0.0001412622,0.00000589377,0.00002570062,0.00001107177,0.00002014027],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5501239,"threshold_uncertainty_score":0.4033567,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01974050658821236,"score_gpt":0.2856410806601167,"score_spread":0.2659005740719044,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}