{"id":"W2594442364","doi":"10.1182/blood.v128.22.675.675","title":"Final Results of a Phase 2 Trial of Extended Treatment (tx) with Carfilzomib (CFZ), Lenalidomide (LEN), and Dexamethasone (KRd) Plus Autologous Stem Cell Transplantation (ASCT) in Newly Diagnosed Multiple Myeloma (NDMM)","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Carfilzomib; Lenalidomide; Multiple myeloma; Medicine; Autologous stem-cell transplantation; Transplantation; Dexamethasone; Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002841145,0.0003155507,0.0008445547,0.0002966661,0.00004250886,0.000008901651,0.00009030612,0.000140957,0.00001819431],"category_scores_gemma":[0.0001428661,0.0001885073,0.0001258697,0.0002223453,0.0001892623,0.0001064355,0.00001817614,0.0001015197,0.000003976831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001362696,"about_ca_system_score_gemma":0.0004176544,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001465515,"about_ca_topic_score_gemma":0.001212851,"domain_scores_codex":[0.9976326,0.0002461084,0.0007046874,0.0005134796,0.0004609975,0.0004420897],"domain_scores_gemma":[0.9978607,0.001062743,0.0002964184,0.0004035693,0.0001210319,0.000255549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6993887,0.01399575,0.02335728,0.0004617957,0.0007692593,0.00341309,0.002755454,0.00001005085,0.09428513,0.000009034282,0.00001523771,0.1615392],"study_design_scores_gemma":[0.6263187,0.01390046,0.05734098,0.0003885764,0.0005178221,0.0001074877,0.0001621931,0.0001186397,0.3009685,0.000007312317,0.00002234698,0.0001469998],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961044,0.0004950209,0.0001453611,0.0001334624,0.00003323685,0.002216511,0.0006070886,0.00003281554,0.0002321714],"genre_scores_gemma":[0.9961222,0.0009554835,0.002137293,0.000006541391,0.00005177385,0.0002398748,0.0001024394,0.00003122537,0.0003531261],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2066834,"threshold_uncertainty_score":0.7687104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03761855174225196,"score_gpt":0.3001488602801984,"score_spread":0.2625303085379465,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}