{"id":"W2594442364","doi":"10.1182/blood.v128.22.675.675","title":"Final Results of a Phase 2 Trial of Extended Treatment (tx) with Carfilzomib (CFZ), Lenalidomide (LEN), and Dexamethasone (KRd) Plus Autologous Stem Cell Transplantation (ASCT) in Newly Diagnosed Multiple Myeloma (NDMM)","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Carfilzomib; Lenalidomide; Multiple myeloma; Medicine; Autologous stem-cell transplantation; Transplantation; Dexamethasone; Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00264191,0.001263286,0.001918042,0.0002934288,0.0004603188,0.001077267,0.0008525833,0.001085549,0.002610691],"category_scores_gemma":[0.001041554,0.0005192145,0.001289704,0.0003005748,0.0008760614,0.0007995809,0.0004891246,0.002866436,0.0006450373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009276227,"about_ca_system_score_gemma":0.001303023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008532559,"about_ca_topic_score_gemma":0.002356662,"domain_scores_codex":[0.9993597,0.0003325456,0.00003429874,0.0000992467,0.00005481367,0.0001194369],"domain_scores_gemma":[0.999211,0.0001091721,0.0001291672,0.0000928993,0.0000496719,0.0004082033],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7831414,0.07810957,0.008644029,0.0004806597,0.001528041,0.0003438542,0.0002799469,0.002210403,0.04109464,0.0002521373,0.00450306,0.0794123],"study_design_scores_gemma":[0.4521742,0.5178918,0.01956843,0.00003253071,0.0007471532,0.0003291667,0.00005528228,0.0008365956,0.00461451,0.0002890103,0.003430012,0.00003138776],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915364,0.001801098,0.0006373855,0.0005271026,0.0001436103,0.002143051,0.001583746,0.00007204291,0.001555576],"genre_scores_gemma":[0.9898,0.0008951008,0.001814562,0.0007287411,0.0001429221,0.001646656,0.002939158,0.00002288442,0.002009842],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00264191,"threshold_uncertainty_score":0.01397198,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03761855174225196,"score_gpt":0.3001488602801984,"score_spread":0.2625303085379465,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}