{"id":"W2594451640","doi":"10.3390/molecules22030383","title":"In Vitro Selection of DNA Aptamers that Binds Geniposide","year":2017,"lang":"en","type":"article","venue":"Molecules","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"China Scholarship Council; Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"Aptamer; Genipin; Gardenia jasminoides; Gardenia; Chemistry; Systematic evolution of ligands by exponential enrichment; In vitro; DNA; Computational biology; Biochemistry; Molecular biology; Biology; Traditional Chinese medicine; RNA; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003337796,0.0005530397,0.000417575,0.0002223686,0.0001131562,0.0002865725,0.0002736293,0.0003800608,0.0006835219],"category_scores_gemma":[0.0005521541,0.0002306421,0.0002196883,0.0002001302,0.0001794958,0.000140038,0.0002750579,0.000585199,0.0005312888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001821114,"about_ca_system_score_gemma":0.0001099795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002558727,"about_ca_topic_score_gemma":0.0005098588,"domain_scores_codex":[0.9995484,0.0001270054,0.00004272762,0.0001057438,0.00009884487,0.00007721833],"domain_scores_gemma":[0.999655,0.0001334205,0.00007951835,0.00002982812,0.00005406405,0.00004818578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000128461,0.00001046884,0.00003914708,0.000009578512,0.000001896313,0.000009096905,0.000009186027,0.00004941217,0.999348,0.00001283109,0.00001126152,0.0004862807],"study_design_scores_gemma":[0.000004309381,0.00009437968,0.0003355848,0.000001948275,0.000006880384,0.00004397241,0.000006907076,0.000584674,0.998164,0.00001109382,0.0007433664,0.000002862793],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9377347,0.001236966,0.05755411,0.0001846233,0.00008736947,0.0002834412,0.0004963914,0.0002783147,0.002144102],"genre_scores_gemma":[0.9457926,0.001044156,0.04543371,0.0002798543,0.00004418464,0.0002734111,0.001697384,0.0001233265,0.005311396],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006835219,"threshold_uncertainty_score":0.002286613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01127843604527787,"score_gpt":0.2762097628881653,"score_spread":0.2649313268428874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}