{"id":"W2594547894","doi":"10.1111/jre.12448","title":"Platelet factor 4 upregulates matrix metalloproteinase‐1 production in gingival fibroblasts","year":2017,"lang":"en","type":"article","venue":"Journal of Periodontal Research","topic":"Oral microbiology and periodontitis research","field":"Dentistry","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Centre for Blood Research, University of British Columbia; University of British Columbia","keywords":"Proinflammatory cytokine; Periodontitis; MAPK/ERK pathway; Matrix metalloproteinase; Inflammation; Collagenase; Immunology; Cytokine; Secretion; Medicine; Cancer research; Chemistry; Kinase; Cell biology; Biology; Internal medicine; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001619937,0.0003477323,0.0002070763,0.0002896045,0.0001688624,0.0002529769,0.00008345138,0.0002133889,0.001498553],"category_scores_gemma":[0.0001245096,0.0001363116,0.0003201719,0.0001896921,0.0001643073,0.0001282143,0.0001844754,0.0004273301,0.0003276137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000230251,"about_ca_system_score_gemma":0.0001979298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008076706,"about_ca_topic_score_gemma":0.0007816744,"domain_scores_codex":[0.9998299,0.00003370786,0.00001427615,0.00001768985,0.00004676875,0.00005764791],"domain_scores_gemma":[0.999925,0.00002778476,0.00001622449,0.000007822894,0.00001053714,0.00001262213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003754836,0.00006719144,0.0003082823,0.000115718,0.0000064298,0.0001627633,0.00003712579,0.00004192364,0.9968939,0.0000404555,0.0001162613,0.001834358],"study_design_scores_gemma":[0.0001202939,0.002199919,0.01853152,0.00002590303,0.00005314896,0.0006163128,0.0001671427,0.000995008,0.9724749,0.0001025509,0.004702199,0.00001108537],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926082,0.004230252,0.0009907039,0.000145084,0.00006180572,0.00004535164,0.0003339757,0.00004567493,0.001538961],"genre_scores_gemma":[0.9930808,0.002686279,0.001420604,0.00009084844,0.00004359775,0.00009208999,0.0004979069,0.000004995349,0.002082814],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001498553,"threshold_uncertainty_score":0.005013168,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08415780456259998,"score_gpt":0.4282488143241793,"score_spread":0.3440910097615793,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}