{"id":"W2594557111","doi":"10.1016/j.bbalip.2017.02.015","title":"Characterization and cellular localization of human 5-lipoxygenase and its protein isoforms 5-LOΔ13, 5-LOΔ4 and 5-LOp12","year":2017,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut Universitaire de Cardiologie et de Pneumologie de Québec; Université Laval","funders":"Else Kröner-Fresenius-Stiftung; Deutsche Forschungsgemeinschaft","keywords":"Gene isoform; Colocalization; Arachidonate 5-lipoxygenase; Molecular biology; Transfection; Cytosol; HEK 293 cells; Exon; Isozyme; Mutant; Subcellular localization; Biology; Cell culture; Chemistry; Cell biology; Enzyme; Biochemistry; Gene; Cytoplasm","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001526399,0.0001894376,0.0001291136,0.0002434375,0.0001980472,0.0002260282,0.0001896024,0.0001954543,0.001122479],"category_scores_gemma":[0.0001863736,0.0001561057,0.0003154354,0.0002285396,0.0001906278,0.0001826477,0.0001714472,0.0002862192,0.0006218739],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000219464,"about_ca_system_score_gemma":0.0001698742,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009509465,"about_ca_topic_score_gemma":0.0007157336,"domain_scores_codex":[0.9999121,0.00001169749,0.00001062382,0.00002788682,0.00001328396,0.00002446499],"domain_scores_gemma":[0.99985,0.00003546999,0.00003051709,0.00002859808,0.00002547907,0.00002987895],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004056136,0.00002800393,0.001551169,0.00003831314,0.00001028522,0.0001433757,0.00004392971,0.00005025957,0.9959552,0.0001737068,0.00003667452,0.001563426],"study_design_scores_gemma":[0.00006458091,0.000495385,0.05826188,0.00001445252,0.0000909049,0.002443473,0.0002886963,0.001774738,0.927641,0.0003152182,0.008595802,0.00001386434],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942536,0.001441752,0.003000093,0.00008100856,0.00001415058,0.0000150053,0.0006447209,0.00001315592,0.0005365406],"genre_scores_gemma":[0.9874307,0.0009621597,0.003621851,0.00005536955,0.00001987907,0.0000460655,0.004282571,0.0000166405,0.003564714],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001122479,"threshold_uncertainty_score":0.003755033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00981335104763425,"score_gpt":0.252843778813687,"score_spread":0.2430304277660528,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}