{"id":"W2594696338","doi":"10.15252/embr.201642377","title":"Cep78 controls centrosome homeostasis by inhibiting EDD‐DYRK2‐DDB1VprBP","year":2017,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Centrosome; Cell biology; Ubiquitin; Biology; Centriole; Centrosome cycle; Phosphorylation; Immunoprecipitation; Cell cycle; Microtubule; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001988382,0.000452828,0.0003738297,0.0003745656,0.0003388072,0.0009838571,0.0007916167,0.0004812397,0.003246143],"category_scores_gemma":[0.0004049495,0.0002587203,0.0002364476,0.000175272,0.0006109736,0.00058477,0.0005323995,0.001136323,0.001652523],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009817221,"about_ca_system_score_gemma":0.000386211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007603745,"about_ca_topic_score_gemma":0.001266452,"domain_scores_codex":[0.9996613,0.00003355705,0.00003209156,0.00007902151,0.0001020572,0.00009202198],"domain_scores_gemma":[0.9997614,0.00003507578,0.0000735038,0.00003318572,0.00002341581,0.00007347731],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005138145,0.00006290949,0.0003791309,0.000067489,0.00002046683,0.000269729,0.00002033723,0.0002854539,0.991143,0.00103844,0.0008561726,0.005343057],"study_design_scores_gemma":[0.00008171931,0.0000761261,0.00325217,0.000007404416,0.0000228355,0.0005359564,0.00005496917,0.002754173,0.9840729,0.0002370762,0.008893086,0.00001159769],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9769266,0.003820961,0.00620633,0.001274565,0.0003472547,0.00004546306,0.001624484,0.0007675274,0.008986733],"genre_scores_gemma":[0.9936084,0.00061465,0.001432719,0.0001093676,0.00002190412,0.00003380955,0.0006165901,0.0001290648,0.003433535],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003246143,"threshold_uncertainty_score":0.01085937,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007028348032361073,"score_gpt":0.2480163793022102,"score_spread":0.2409880312698491,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}