{"id":"W2594759564","doi":"10.1126/scitranslmed.aaf6397","title":"Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice","year":2017,"lang":"en","type":"article","venue":"Science Translational Medicine","topic":"Gastrointestinal motility and disorders","field":"Medicine","cited_by":506,"is_retracted":false,"has_abstract":true,"ca_institutions":"Wilfrid Laurier University; University of Waterloo; McMaster University; Population Health Research Institute","funders":"Canadian Institutes of Health Research; Hamilton Health Sciences","keywords":"Irritable bowel syndrome; Gut flora; Feces; Transplantation; Fecal bacteriotherapy; Medicine; Gastroenterology; Gut–brain axis; Internal medicine; Immunology; Biology; Microbiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002844069,0.0001064465,0.0001977349,0.0001838013,0.0001692092,0.0000130946,0.0001095497,0.00002813783,0.00006179999],"category_scores_gemma":[0.00008125718,0.00008132606,0.00001834464,0.0001528809,0.001126779,0.0003576441,0.000006631426,0.0001141831,0.000001423095],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002577664,"about_ca_system_score_gemma":0.00009773405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009809107,"about_ca_topic_score_gemma":0.0003244641,"domain_scores_codex":[0.9987633,0.00001430398,0.0002523287,0.0003048985,0.0004897913,0.0001754055],"domain_scores_gemma":[0.9994114,0.00005802512,0.0001070975,0.0001660771,0.0001410888,0.0001162979],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008605249,0.0002365198,0.9525901,0.00006374755,0.00000552998,0.0000100857,0.0003992592,0.00001719608,0.04444736,0.00006098725,0.000003156048,0.001305495],"study_design_scores_gemma":[0.004905313,0.0008756989,0.9926975,0.0005561483,0.0001377248,0.00003615482,0.00009841231,0.0001474535,0.0002080203,0.0002702744,0.000002574836,0.00006477621],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965283,0.00005613304,0.0007317858,0.001896111,0.0001204657,0.0003800154,0.00004022955,0.000007723222,0.0002392977],"genre_scores_gemma":[0.9978979,0.000008273028,0.001886368,0.00007178537,0.00001447917,0.000008214676,0.00009521774,0.000005403811,0.00001238551],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04423934,"threshold_uncertainty_score":0.4151663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0153145282012197,"score_gpt":0.2596955920937091,"score_spread":0.2443810638924894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}