{"id":"W2594810701","doi":"10.1093/neuonc/now293.021","title":"PP22. PROGRESSING RADIOTHERAPY-DRUG COMBINATIONS TOWARDS EARLY PHASE CLINICAL TRIALS","year":2017,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Drug Research and Development","funders":"","keywords":"Context (archaeology); Radiation therapy; Alliance; Clinical trial; Medicine; Drug development; Quality (philosophy); Medical physics; Drug; Pharmacology; Political science; Surgery; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.02262635,0.0009893473,0.0009020147,0.001628174,0.001326852,0.01099664,0.001855603,0.005685225,0.3062427],"category_scores_gemma":[0.02197635,0.0007308522,0.001326143,0.00183523,0.001942573,0.005250779,0.005088704,0.005256557,0.270189],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004260771,"about_ca_system_score_gemma":0.01159902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002636831,"about_ca_topic_score_gemma":0.006199799,"domain_scores_codex":[0.9886178,0.003854868,0.0007828317,0.0006376537,0.005181543,0.0009253586],"domain_scores_gemma":[0.9765766,0.004765416,0.001320205,0.001946784,0.008908657,0.00648236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001314615,0.00006992381,0.0001988954,0.0004826158,0.000007258506,0.00009442933,0.00005632517,0.00009405644,0.0005034649,0.01065638,0.8945969,0.09310822],"study_design_scores_gemma":[0.00006403847,0.0001157774,0.0005471484,0.0002167263,0.000004311392,0.0001083699,0.00002292222,0.00005019099,0.0001914755,0.002840921,0.9958292,0.000008883831],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.001422309,0.02139164,0.00973137,0.09346928,0.02569262,0.002609366,0.009254862,0.0028896,0.8335388],"genre_scores_gemma":[0.01390176,0.03939258,0.02133681,0.07592183,0.02374018,0.003557104,0.01529031,0.00272295,0.8041365],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.3062427,"threshold_uncertainty_score":0.9895605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0994381586591382,"score_gpt":0.4701017286600177,"score_spread":0.3706635700008795,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}