{"id":"W2594859485","doi":"10.1158/1538-7445.sabcs16-p4-07-06","title":"Abstract P4-07-06: MicroRNAs associated with acquired taxane resistance in a breast cancer cell line model","year":2017,"lang":"en","type":"article","venue":"Cancer Research","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research; University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"microRNA; Paclitaxel; Taxane; Fold change; Breast cancer; Drug resistance; Cancer research; Biology; Cancer; Downregulation and upregulation; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002900043,0.0003185645,0.0004086761,0.0003996245,0.0002378724,0.0003574087,0.0002757567,0.0004611876,0.00341331],"category_scores_gemma":[0.0001981237,0.0001994471,0.0004118986,0.0003604876,0.0002054014,0.0001885431,0.0002029161,0.0009985199,0.001244217],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003521192,"about_ca_system_score_gemma":0.0002894372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008919358,"about_ca_topic_score_gemma":0.0008323023,"domain_scores_codex":[0.9995952,0.00004786408,0.00004628448,0.00008070423,0.0001787762,0.00005119171],"domain_scores_gemma":[0.9997976,0.00004441917,0.00004064975,0.00003623679,0.00004486868,0.00003629095],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001811629,0.0001808976,0.0005150947,0.00003950014,0.000009633199,0.0001141382,0.00002470089,0.00009684308,0.9969413,0.0000754468,0.0003230126,0.001498362],"study_design_scores_gemma":[0.00003049174,0.001213575,0.006176877,0.000005321671,0.00003064017,0.0006933805,0.000054124,0.001753239,0.9860594,0.00004897191,0.003927101,0.000006990349],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853107,0.0006978563,0.006037871,0.0002568083,0.0001032498,0.0002087912,0.003660714,0.0002697194,0.003454262],"genre_scores_gemma":[0.9667072,0.0007877938,0.009828298,0.0001922717,0.00002453826,0.0005173692,0.00818497,0.00009857096,0.01365907],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00341331,"threshold_uncertainty_score":0.0114187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04152032540265908,"score_gpt":0.3547081671602331,"score_spread":0.313187841757574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}