{"id":"W2594905547","doi":"10.1007/978-1-4939-6857-2_10","title":"Antibody Validation by Immunoprecipitation Followed by Mass Spectrometry Analysis","year":2017,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Wellcome Trust","keywords":"Immunoprecipitation; Antibody; Mass spectrometry; Chemistry; Computational biology; Antigen; RNA; Molecular biology; Antibody microarray; Biology; Biochemistry; Chromatography; Gene; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005629407,0.0001484739,0.0002908864,0.0001287264,0.0001538366,0.00004714806,0.000470386,0.0002396319,0.0001376178],"category_scores_gemma":[0.0002991866,0.0001579988,0.0001350491,0.0002340445,0.00009740505,0.00005724136,0.00008622752,0.000211219,0.000003168882],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006941643,"about_ca_system_score_gemma":0.000009990931,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008322143,"about_ca_topic_score_gemma":0.000001210162,"domain_scores_codex":[0.9988548,0.0001566061,0.0002930313,0.000412058,0.00005891096,0.0002246605],"domain_scores_gemma":[0.9986596,0.00009163276,0.0003061898,0.0008695226,0.00003856862,0.0000344681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000008246163,0.0000311551,0.007142362,0.000004996251,0.000100291,9.714075e-7,0.000009828559,0.00001042479,0.9887496,0.00131006,0.00002726911,0.002604835],"study_design_scores_gemma":[0.0002029365,0.00001634756,0.0001175461,0.000003814068,0.00008514285,5.655007e-7,0.00001163717,0.0004512667,0.9689714,0.02793557,0.002034409,0.0001693514],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.04497432,0.000285623,0.9510667,0.0001871967,0.00002662369,0.0001134056,0.00006238076,0.00005299723,0.003230711],"genre_scores_gemma":[0.0880612,0.0001326197,0.9102322,0.00003608318,0.00001229309,0.0001192936,0.001121552,0.00001833706,0.0002663929],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.04308688,"threshold_uncertainty_score":0.6443004,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01370040155698267,"score_gpt":0.427713654201949,"score_spread":0.4140132526449663,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}