{"id":"W2595078522","doi":"10.1093/biolreprod/78.s1.121a","title":"Assessment of the Developmental Potential of Rat Embryonic Stem-Like (ES-Like) Cells by Diploid and Tetraploid Embryo Aggregation Confirms Their In Vivo Multipotency.","year":2008,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Biology; Embryonic stem cell; Blastocyst; Embryo; Chimera (genetics); Cell biology; Stem cell; Transfection; Ploidy; Embryogenesis; Inner cell mass; Genetics; Molecular biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004093058,0.0004876193,0.0002215492,0.0005392486,0.0001582775,0.0002269271,0.0002379515,0.0003516043,0.001175816],"category_scores_gemma":[0.0002641361,0.0001494288,0.0003088261,0.0002157638,0.0002221245,0.0002451258,0.000335236,0.0004337776,0.0005984138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001203045,"about_ca_system_score_gemma":0.0001280613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003131886,"about_ca_topic_score_gemma":0.0005045559,"domain_scores_codex":[0.9996849,0.00006969333,0.00005895222,0.0000797631,0.00007214316,0.00003452312],"domain_scores_gemma":[0.9995872,0.0001431524,0.00008992445,0.00007633405,0.00004077132,0.00006258639],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002223771,0.000008403071,0.0003161928,0.00001678158,0.000002434243,0.00004353745,0.00001704033,0.00002196604,0.9984555,0.00004972138,0.000007519724,0.001038614],"study_design_scores_gemma":[0.00000425036,0.000348993,0.007904214,0.000005132773,0.00002264586,0.0004623042,0.00002681176,0.0003019765,0.9891536,0.00005410987,0.001708712,0.000007295044],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9241417,0.003838057,0.06396039,0.00008588403,0.00004305616,0.0002366089,0.001280622,0.0003305797,0.006083078],"genre_scores_gemma":[0.945578,0.002806972,0.04418024,0.0000621123,0.00001373173,0.0002436398,0.002297472,0.00009870711,0.004719063],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001175816,"threshold_uncertainty_score":0.003933489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0119475002436502,"score_gpt":0.244651595648166,"score_spread":0.2327040954045158,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}