{"id":"W2595233297","doi":"10.1074/jbc.m117.775569","title":"A unique choanoflagellate enzyme rhodopsin exhibits light-dependent cyclic nucleotide phosphodiesterase activity","year":2017,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Photoreceptor and optogenetics research","field":"Neuroscience","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Ministry of Education, Culture, Sports, Science and Technology","keywords":"Rhodopsin; Phosphodiesterase; Nucleotide; Enzyme; Cyclic nucleotide phosphodiesterase; Chemistry; Biochemistry; Biology; Cell biology; Gene; Retinal","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000620444,0.000230803,0.000392181,0.00003358069,0.0003998346,0.0002766793,0.001278675,0.0002482927,0.0004906803],"category_scores_gemma":[0.002451363,0.0001590909,0.0002379484,0.00006505439,0.0003048521,0.000199101,0.0004256073,0.0007913035,0.0000350496],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001131905,"about_ca_system_score_gemma":0.0001027577,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000790575,"about_ca_topic_score_gemma":0.00000107012,"domain_scores_codex":[0.9981255,0.0001586639,0.0004032654,0.0003756232,0.0004731019,0.0004638515],"domain_scores_gemma":[0.998029,0.0002720295,0.000640485,0.0005405719,0.0001183326,0.0003995727],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003094563,0.000192116,0.00181362,0.00001942181,0.00001031945,0.0003623653,0.00002904171,0.000004799957,0.9954261,0.00000398001,0.000231653,0.001597146],"study_design_scores_gemma":[0.0006016002,0.0001589211,0.003875704,0.00004589287,0.00000677655,0.0002349409,0.00001104975,0.00003402245,0.9917017,0.0002385735,0.00289819,0.0001926588],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912512,0.0001045942,0.00004629541,0.000599708,0.0002177111,0.00009878804,0.00001821484,0.00002097579,0.007642484],"genre_scores_gemma":[0.997933,0.0007969908,0.0001111939,0.0001333942,0.0003057164,0.000003413051,4.382143e-7,0.00001527761,0.0007005334],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006941951,"threshold_uncertainty_score":0.6487538,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07353723322408032,"score_gpt":0.3312166495433955,"score_spread":0.2576794163193152,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}