{"id":"W2595416856","doi":"10.1200/jco.2007.25.18_suppl.7522","title":"Randomized phase II study of maintenance vandetanib (ZD6474) in small cell lung cancer (SCLC) patients who have a complete or partial response to induction therapy: NCIC CTG BR.20","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Lung Cancer Research Studies","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Juravinski Cancer Centre; Sunnybrook Health Science Centre; Niagara Health System; BC Cancer Agency","funders":"","keywords":"Medicine; Internal medicine; Vandetanib; Gastroenterology; Hazard ratio; Asymptomatic; Progressive disease; Rash; Maintenance therapy; Performance status; Progression-free survival; Surgery; Chemotherapy; Confidence interval; Sorafenib","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00134286,0.001243394,0.002048429,0.0003827753,0.0003772446,0.0008186139,0.0008502359,0.001214006,0.005302081],"category_scores_gemma":[0.001219595,0.0006300311,0.0006837738,0.0004078161,0.000820367,0.0005465097,0.0003354952,0.00213128,0.0009762467],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009886746,"about_ca_system_score_gemma":0.001525836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001767774,"about_ca_topic_score_gemma":0.004798527,"domain_scores_codex":[0.9996439,0.0001905031,0.00001605385,0.00005193567,0.00003020432,0.00006744552],"domain_scores_gemma":[0.9993261,0.0001214644,0.0001420425,0.00004511292,0.00003517646,0.0003301493],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9410298,0.01538582,0.003015143,0.0003771021,0.0005914284,0.0001242401,0.00007901271,0.0007664969,0.00790135,0.0001426578,0.003039784,0.02754709],"study_design_scores_gemma":[0.9340834,0.06151624,0.002827873,0.00001009335,0.0001184502,0.00004818113,0.00001034903,0.000345084,0.0003084288,0.00005980521,0.000665918,0.000006155567],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882495,0.001959678,0.0004808034,0.0006568417,0.0002465545,0.005102664,0.001458007,0.0001237787,0.001722181],"genre_scores_gemma":[0.983478,0.001421724,0.001503685,0.001387072,0.0002577662,0.005343223,0.002401332,0.00002703107,0.004180209],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005302081,"threshold_uncertainty_score":0.01773721,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1979454474880691,"score_gpt":0.5368576189100606,"score_spread":0.3389121714219914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}