{"id":"W2595991414","doi":"10.1016/j.ccell.2017.02.010","title":"Integrated Molecular Characterization of Uterine Carcinosarcoma","year":2017,"lang":"en","type":"article","venue":"Cancer Cell","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":444,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; BC Cancer Agency","funders":"National Cancer Institute; National Human Genome Research Institute; National Institutes of Health","keywords":"PTEN; Biology; Somatic cell; Carcinosarcoma; KRAS; Epigenetics; Cancer research; Transcriptome; Epigenomics; Gene; GNAQ; Serous fluid; DNA methylation; Carcinoma; Genetics; Mutation; PI3K/AKT/mTOR pathway; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000209335,0.00008145347,0.0001778865,0.00001907384,0.00004160409,0.00001297061,0.00007458265,0.00003340305,0.000433308],"category_scores_gemma":[0.000007169881,0.0000643515,0.00005657861,0.00002188843,0.00003744474,0.00005037648,0.00002830138,0.00003557814,0.000008525853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006499856,"about_ca_system_score_gemma":0.00005160185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006774588,"about_ca_topic_score_gemma":0.00002705259,"domain_scores_codex":[0.9995689,0.000007659522,0.0001148399,0.0001261145,0.00008764026,0.00009487617],"domain_scores_gemma":[0.9993555,0.000004267523,0.0001146588,0.0003915642,0.00007850809,0.00005549732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004769288,0.0002084672,0.2882515,0.00008074708,0.00004028057,0.00008782806,0.00006168895,2.11944e-7,0.6894518,0.00005615721,0.0000811962,0.02163248],"study_design_scores_gemma":[0.0007906507,0.00006190537,0.4348609,0.00005920785,0.00004727919,0.000003002912,0.000007543761,0.00004442866,0.5533012,0.00000508361,0.01077725,0.0000415698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994994,0.0008062983,0.00005727461,0.0004859528,0.0001979417,0.0001810134,0.00003906045,0.00001315701,0.003225341],"genre_scores_gemma":[0.99813,0.0005660614,0.0001321918,0.0001550244,0.00004628842,0.00004538174,0.00005938831,0.00001295473,0.0008527311],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1466094,"threshold_uncertainty_score":0.4744419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02238540813939906,"score_gpt":0.3003475547202094,"score_spread":0.2779621465808103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}