{"id":"W2596168750","doi":"10.1182/blood.v128.22.1126.1126","title":"Exploring the Potential of JAK1/2 Inhibitor Ruxolitinib with Reduced Intensity Hematopoietic Cell Transplantation (HCT) for Myelofibrosis: Stage I Results of a Prospective Trial Conducted through the Myeloproliferative Disorders - Research Consortium (MPD-RC)","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Ruxolitinib; Myelofibrosis; Medicine; Internal medicine; Transplantation; Fludarabine; Regimen; Hematopoietic stem cell transplantation; Clinical trial; Surgery; Busulfan; Gastroenterology; Oncology; Bone marrow; Chemotherapy; Cyclophosphamide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005343649,0.0008749265,0.001305789,0.0002165112,0.0002914581,0.001483119,0.0006705863,0.00116589,0.002531884],"category_scores_gemma":[0.00192493,0.0003167113,0.001954041,0.0001970253,0.0007314856,0.0008712141,0.0003810216,0.002574154,0.000506002],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004846345,"about_ca_system_score_gemma":0.0009845749,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002223563,"about_ca_topic_score_gemma":0.0008472205,"domain_scores_codex":[0.998697,0.0008952785,0.0000800398,0.0001121675,0.00007863614,0.000136948],"domain_scores_gemma":[0.9984793,0.0004294049,0.0003572252,0.0001822304,0.00008199827,0.0004697944],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.812029,0.03567009,0.01284658,0.0007834982,0.001885577,0.0002709849,0.0002812791,0.002120349,0.03622985,0.0008806838,0.00245114,0.09455089],"study_design_scores_gemma":[0.4351909,0.5336995,0.01676682,0.00008802203,0.001693413,0.0002661612,0.00009217595,0.001694456,0.006665364,0.0005259107,0.003274899,0.00004237153],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920943,0.003168412,0.0007517094,0.0009068189,0.0001370128,0.001057252,0.000498276,0.00002966167,0.001356537],"genre_scores_gemma":[0.9939208,0.0013078,0.001259834,0.0008355786,0.0001497881,0.0006723969,0.0007480594,0.00001156897,0.001094243],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005343649,"threshold_uncertainty_score":0.02826023,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07615313580450668,"score_gpt":0.3119131294828535,"score_spread":0.2357599936783469,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}