{"id":"W2596264928","doi":"10.1038/cti.2017.4","title":"Understanding CD8<sup>+</sup> T‐cell responses toward the native and alternate HLA‐A∗02:01‐restricted WT1 epitope","year":2017,"lang":"en","type":"article","venue":"Clinical & Translational Immunology","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Emergent BioSolutions (Canada)","funders":"","keywords":"Epitope; Immunogenicity; Cytotoxic T cell; Biology; CD8; T cell; Human leukocyte antigen; Immunology; Antigen; Virology; Immune system; Molecular biology; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003751103,0.0001883893,0.0002437494,0.0000418447,0.0004945162,0.00006706169,0.0004609633,0.0004124166,0.0000324483],"category_scores_gemma":[0.0003190211,0.0001329519,0.0001794337,0.00004699612,0.001184668,0.00001485189,0.0001126969,0.0004594852,0.00001405951],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001926036,"about_ca_system_score_gemma":0.0001749953,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004131861,"about_ca_topic_score_gemma":0.00001273639,"domain_scores_codex":[0.9983708,0.0003233755,0.0004534902,0.000439196,0.0001388153,0.0002743325],"domain_scores_gemma":[0.9987941,0.0004152315,0.0002249248,0.0004114511,0.0000807976,0.00007345053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0344492,0.001557152,0.1957384,0.0002141303,0.01017942,0.0003399999,0.005340692,0.006900043,0.6085373,0.04473328,0.008590314,0.08342011],"study_design_scores_gemma":[0.0291708,0.006593842,0.6268116,0.0003608396,0.0009860353,0.0005181071,0.002903229,0.007308495,0.07808921,0.07584699,0.1684434,0.002967451],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9778181,0.005237904,0.002329533,0.01095707,0.0005116402,0.0002529577,0.00005563304,0.00001763131,0.002819475],"genre_scores_gemma":[0.9911574,0.00718158,0.0001439074,0.0004040998,0.0002791976,0.00001188282,0.00006052511,0.00001900503,0.0007424082],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5304481,"threshold_uncertainty_score":0.5421621,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1111220680898226,"score_gpt":0.3576766543172875,"score_spread":0.2465545862274649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}