{"id":"W2596264928","doi":"10.1038/cti.2017.4","title":"Understanding CD8<sup>+</sup> T‐cell responses toward the native and alternate HLA‐A∗02:01‐restricted WT1 epitope","year":2017,"lang":"en","type":"article","venue":"Clinical & Translational Immunology","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Emergent BioSolutions (Canada)","funders":"","keywords":"Epitope; Immunogenicity; Cytotoxic T cell; Biology; CD8; T cell; Human leukocyte antigen; Immunology; Antigen; Virology; Immune system; Molecular biology; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001279103,0.0002459626,0.0001114608,0.00007601377,0.00007741775,0.0003422184,0.0001538356,0.0004719075,0.00133693],"category_scores_gemma":[0.0001004707,0.0001083788,0.0001015933,0.00004268531,0.0001516102,0.0004775167,0.000133906,0.0005442817,0.0004357637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001519207,"about_ca_system_score_gemma":0.00007527749,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001800747,"about_ca_topic_score_gemma":0.0003089722,"domain_scores_codex":[0.9999465,0.000008619594,0.000004380496,0.00001544566,0.000008319764,0.00001674125],"domain_scores_gemma":[0.9999701,0.00000783074,0.000007793408,0.00000265102,0.000004404418,0.000007330801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002578816,0.00004408609,0.001194692,0.0001056669,0.000003050748,0.00008541023,0.00005258235,0.0003770764,0.9924254,0.0001742398,0.0001052331,0.005174566],"study_design_scores_gemma":[0.0000851115,0.001690828,0.06349225,0.00004857015,0.00006498703,0.002308179,0.00069607,0.01567605,0.9049496,0.001541046,0.009428634,0.00001863],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923096,0.001791456,0.003534276,0.0003432145,0.00001826828,0.0000246546,0.0001660193,0.00004271098,0.001769864],"genre_scores_gemma":[0.9949585,0.001159153,0.002010929,0.0002485158,0.0000482675,0.00003191044,0.000205908,0.000007868624,0.001329023],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00133693,"threshold_uncertainty_score":0.004472494,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1111220680898226,"score_gpt":0.3576766543172875,"score_spread":0.2465545862274649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}