{"id":"W2596280424","doi":"10.1101/115972","title":"CaMK (CMK-1) and O-GlcNAc transferase (OGT-1) modulate mechanosensory responding and habituation in an interstimulus interval-dependent manner in <i>Caenorhabditis elegans</i>","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kinexus Bioinformatics Corporation (Canada); University of British Columbia; University of British Columbia Hospital","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Habituation; Caenorhabditis elegans; Mechanosensation; Biology; Neuroscience; CAMK; Interstimulus interval; Cell biology; Mutant; Gene knockdown; Associative learning; Genetics; Protein kinase A; Kinase; Autophosphorylation; Gene; Stimulation; Ion channel","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004090878,0.000300653,0.0001398061,0.0001245975,0.0001184338,0.0001448444,0.000272937,0.0002031973,0.0008122052],"category_scores_gemma":[0.00007069655,0.0001279978,0.0001714598,0.00006320966,0.0002358031,0.0001041998,0.0001670142,0.0005153389,0.000131935],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004034863,"about_ca_system_score_gemma":0.0001477559,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002052122,"about_ca_topic_score_gemma":0.00362847,"domain_scores_codex":[0.999951,0.000002081361,0.000002904482,0.00001290324,0.00001242497,0.0000187338],"domain_scores_gemma":[0.9999288,0.000005586485,0.00002501197,0.000004336732,0.000007073573,0.00002912262],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006444338,0.00001070348,0.0001912666,0.0000113446,0.000001556587,0.00001734985,0.000002400171,0.00003321291,0.9993838,0.00001684974,0.00001816818,0.0002488629],"study_design_scores_gemma":[0.00002612196,0.0002266097,0.03014181,0.000007326947,0.00001460783,0.0001074751,0.00002425416,0.002966311,0.9656979,0.00006288333,0.0007170849,0.000007600517],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983719,0.0002331867,0.0005811608,0.00003876148,0.00001684001,0.00001202833,0.000147206,0.00005903761,0.0005400248],"genre_scores_gemma":[0.9978897,0.0001777307,0.0006326108,0.0000537016,0.000002927463,0.00002263376,0.0001313844,0.00001008572,0.001079159],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002052122,"threshold_uncertainty_score":0.004080355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01237435324392979,"score_gpt":0.2309195003274335,"score_spread":0.2185451470835037,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}