{"id":"W2596416589","doi":"10.1093/biolreprod/87.s1.96","title":"Folate Deficiency Alters the Sperm Epigenome and Reproductive Outcomes.","year":2012,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université Sainte-Anne","funders":"","keywords":"Epigenome; Biology; Offspring; Epigenetics; Sperm; Spermatogenesis; DNA methylation; Andrology; Histone; Embryo; Germ cell; Genetics; Endocrinology; Pregnancy; Gene expression; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001983984,0.0002509331,0.0002334484,0.0005037047,0.0001729518,0.0002636221,0.0001755893,0.0003445474,0.002074492],"category_scores_gemma":[0.0003123599,0.0001612761,0.0002359092,0.0003034484,0.0001933265,0.00015605,0.0002329041,0.0002144769,0.0002024228],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002707746,"about_ca_system_score_gemma":0.0002142231,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002736747,"about_ca_topic_score_gemma":0.003629166,"domain_scores_codex":[0.9998872,0.00002899211,0.000008243674,0.00003299237,0.00002590616,0.00001669943],"domain_scores_gemma":[0.9998026,0.00002530509,0.0001045212,0.00001566072,0.00002262875,0.00002918679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002231115,0.0001057629,0.1789356,0.0004078271,0.0005241858,0.001067114,0.0002451525,0.0001918891,0.7685091,0.0005210879,0.0005559527,0.04670499],"study_design_scores_gemma":[0.00002368413,0.001627682,0.9404133,0.00005888099,0.0002512487,0.002626589,0.0001654858,0.0002471801,0.04756904,0.0003794454,0.006618355,0.0000191616],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9796603,0.01451379,0.001443924,0.0002627566,0.00001795588,0.00001701563,0.001904192,0.00008241482,0.002097513],"genre_scores_gemma":[0.9907162,0.005027369,0.0007904822,0.00007626177,0.000008570069,0.000009777325,0.0007625322,0.000007696754,0.002601066],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002736747,"threshold_uncertainty_score":0.006939828,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01879857716565006,"score_gpt":0.2797102076968249,"score_spread":0.2609116305311748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}