{"id":"W2596571051","doi":"10.1182/blood.v118.21.5146.5146","title":"Clinical Burden and Progression of Myelofibrosis in a Controlled Study Population of Placebo-Treated Patients (COMFORT-I)","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Medicine; Myelofibrosis; Placebo; Ruxolitinib; Population; Internal medicine; Clinical trial; Surgery; Pathology; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004983875,0.001093274,0.001954802,0.0004331539,0.0004679128,0.0007565283,0.0005915668,0.001261286,0.004522194],"category_scores_gemma":[0.003364855,0.0004862579,0.00132406,0.0004323264,0.0008843641,0.0006224559,0.0005094395,0.0009684473,0.0005112503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004337886,"about_ca_system_score_gemma":0.0008967411,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003256515,"about_ca_topic_score_gemma":0.0004711632,"domain_scores_codex":[0.9976587,0.001366861,0.0002561113,0.0003716843,0.000200466,0.0001461751],"domain_scores_gemma":[0.9976447,0.000640974,0.0007015609,0.0003118649,0.0002361799,0.000464614],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9496684,0.009295785,0.01945002,0.000564172,0.001639148,0.0001097634,0.0001277777,0.0002479093,0.00669123,0.00008468583,0.0005548202,0.01156629],"study_design_scores_gemma":[0.5557454,0.3777338,0.06103346,0.00005398893,0.00169886,0.0002117039,0.00009828782,0.000682122,0.001435816,0.0001106545,0.001159898,0.00003604438],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941077,0.00148314,0.0003307702,0.00007881539,0.0000671358,0.002513073,0.0006735137,0.00002161305,0.0007241835],"genre_scores_gemma":[0.9928085,0.0004306209,0.0007287718,0.0002521074,0.0002194646,0.004075734,0.00107584,0.000005387938,0.0004035347],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004983875,"threshold_uncertainty_score":0.02635753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03565850352619703,"score_gpt":0.3289837847036933,"score_spread":0.2933252811774962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}