{"id":"W2596607108","doi":"10.1093/biolreprod/83.s1.203","title":"Derivation and Characterization of Canine Embryonic Stem Cell Lines with In Vitro and In Vivo Differentiation Potential.","year":2010,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; Sunnybrook Hospital","funders":"","keywords":"Biology; Homeobox protein NANOG; Embryonic stem cell; SOX2; Cell biology; Inner cell mass; Stem cell; Blastocyst; Embryoid body; Cellular differentiation; KOSR; Somatic cell; Rex1; Germ layer; Immunology; Induced pluripotent stem cell; Embryo; Embryogenesis; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009149183,0.0003759653,0.0004408142,0.0007932519,0.0003115302,0.0005259975,0.0005613714,0.0004676941,0.002088071],"category_scores_gemma":[0.0007272932,0.0003212785,0.0003766571,0.0005551957,0.0002838587,0.0002816606,0.0003432121,0.0007046349,0.001630776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000286984,"about_ca_system_score_gemma":0.0005340526,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001094213,"about_ca_topic_score_gemma":0.002577406,"domain_scores_codex":[0.999418,0.00007443081,0.0001212726,0.00007689816,0.0002417956,0.00006758118],"domain_scores_gemma":[0.9992473,0.0001436127,0.0001250364,0.0001471717,0.000240382,0.00009647552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001014126,0.0000765174,0.0008419206,0.0001879251,0.00001105173,0.0002250842,0.0001234315,0.0002758413,0.9902844,0.000794607,0.0005811545,0.006496682],"study_design_scores_gemma":[0.00005906645,0.0007407869,0.008016048,0.00005688958,0.0001063795,0.002112561,0.0001014305,0.002024047,0.9096898,0.0002079923,0.07685771,0.00002727552],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7382445,0.01167475,0.1836775,0.0009243059,0.0005632624,0.004898952,0.03531992,0.001146541,0.02355029],"genre_scores_gemma":[0.6689926,0.01041146,0.2116441,0.0003728861,0.0001270877,0.003119935,0.08304019,0.0004995991,0.02179202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002088071,"threshold_uncertainty_score":0.006985307,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005921357843289673,"score_gpt":0.2174671199059899,"score_spread":0.2115457620627002,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}