{"id":"W2596865928","doi":"10.4049/jimmunol.1601629","title":"The Importance of Dendritic Cells in Maintaining Immune Tolerance","year":2017,"lang":"en","type":"review","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":274,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Clinical Research Institute; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"National Institutes of Health","keywords":"Immune system; Immune tolerance; Peripheral tolerance; Autoimmunity; Immunology; Clonal deletion; Dendritic cell; Central tolerance; Immunity; Biology; Self Tolerance; T cell; T-cell receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.004582794,0.0005183085,0.00290626,0.0003513636,0.0006276667,0.00003373626,0.003461828,0.0007070888,0.0001216498],"category_scores_gemma":[0.0006536466,0.0002709863,0.0009131768,0.0002261996,0.001851054,0.0001502994,0.0003112917,0.002563755,0.00009110515],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001530836,"about_ca_system_score_gemma":0.0008211476,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005787593,"about_ca_topic_score_gemma":0.00002811429,"domain_scores_codex":[0.9929277,0.003199903,0.002859227,0.0001963506,0.00009021458,0.0007265665],"domain_scores_gemma":[0.9893642,0.00367562,0.005216192,0.001509961,0.0002216854,0.00001232202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002158048,0.0001789211,0.0000243895,0.0006986284,0.003071327,0.00007782155,0.0009222208,0.000005657218,0.01653724,0.0007107233,0.0003835043,0.9752315],"study_design_scores_gemma":[0.001288758,0.0005620248,0.0002097206,0.006959393,0.0005049224,0.003470956,0.0004946776,1.860377e-7,0.002517097,0.0001770269,0.9835355,0.0002797881],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003169271,0.992841,0.00001378616,0.0001574612,0.003150836,0.0004396795,0.00001597108,0.000007674187,0.0002043103],"genre_scores_gemma":[0.005569482,0.992435,0.00001582234,0.00002996459,0.00006030542,0.00001673615,0.000006594274,0.00005665185,0.001809419],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.983152,"threshold_uncertainty_score":0.9999743,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03407329120337719,"score_gpt":0.3143773687967299,"score_spread":0.2803040775933527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}