{"id":"W2597223639","doi":"10.1200/jco.2007.25.18_suppl.1099","title":"Randomized phase II study of biweekly gemcitabine (gem)-paclitaxel (pac), gem-carboplatin (carb) and gem-cisplatin (cis) as first-line treatments in metastatic breast cancer (MBC) after anthracycline failure","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Eli Lilly (Canada)","funders":"","keywords":"Medicine; Clinical endpoint; Metastatic breast cancer; Interim analysis; Internal medicine; Carboplatin; Gemcitabine; Anthracycline; Breast cancer; Phases of clinical research; Surgery; Performance status; Chemotherapy; Oncology; Urology; Cancer; Randomized controlled trial; Gastroenterology; Cisplatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003888143,0.002172552,0.00392371,0.0007639883,0.0006075097,0.001481394,0.001615968,0.002294734,0.007859993],"category_scores_gemma":[0.002565491,0.001299397,0.001545115,0.00075196,0.001925102,0.001499014,0.0006283632,0.00513089,0.001674762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001024297,"about_ca_system_score_gemma":0.002538121,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00106384,"about_ca_topic_score_gemma":0.002713306,"domain_scores_codex":[0.998849,0.000725587,0.00005531824,0.0001330622,0.00005848367,0.0001784484],"domain_scores_gemma":[0.9975671,0.0005986029,0.0004128125,0.0002379067,0.0001157356,0.001068019],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9368809,0.0435634,0.0009961228,0.0002453082,0.0004917922,0.00006204173,0.00008975084,0.0005821501,0.005395005,0.0001129021,0.001165301,0.01041537],"study_design_scores_gemma":[0.8705369,0.1264914,0.001242337,0.00001010929,0.0001732941,0.00003536293,0.00001999481,0.0004061249,0.0004872144,0.00009053401,0.0004948326,0.00001205926],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9797204,0.001399513,0.001208493,0.0008557391,0.000585314,0.01205915,0.001844356,0.0002243907,0.002102604],"genre_scores_gemma":[0.9668502,0.001891873,0.00404045,0.002280029,0.0005404977,0.01591753,0.002618324,0.0000891083,0.005772114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007859993,"threshold_uncertainty_score":0.02629435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09059287299246062,"score_gpt":0.5155515087569532,"score_spread":0.4249586357644926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}