{"id":"W2597243443","doi":"10.1182/blood.v106.11.934.934","title":"A Phase II Study of Enzastaurin, a Protein Kinase C-β (PKCβ) Inhibitor, in the Treatment of Relapsed Diffuse Large B-Cell Lymphoma (DLBCL).","year":2005,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Medicine; Internal medicine; Phases of clinical research; Diffuse large B-cell lymphoma; Neutropenia; Febrile neutropenia; Transplantation; Progressive disease; Toxicity; Oncology; Pharmacology; Surgery; Chemotherapy; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001150195,0.0008502395,0.001035171,0.0003298048,0.0002653006,0.0005802208,0.000508431,0.0005803561,0.001694918],"category_scores_gemma":[0.0003882273,0.0003640772,0.0006422132,0.0002759194,0.0004582729,0.0003958815,0.0002073403,0.001670725,0.0003807124],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004841602,"about_ca_system_score_gemma":0.0008653587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000755946,"about_ca_topic_score_gemma":0.002012013,"domain_scores_codex":[0.9997523,0.0001337483,0.00001503799,0.00003622361,0.0000190106,0.00004354418],"domain_scores_gemma":[0.9997104,0.00004196806,0.00005933738,0.00003320894,0.00001973956,0.000135341],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4548904,0.1076722,0.01955557,0.000835985,0.001155246,0.0006186853,0.0003906352,0.003353172,0.2547903,0.0003960677,0.002577892,0.1537638],"study_design_scores_gemma":[0.2770415,0.6786436,0.02106866,0.00003255198,0.0004525803,0.0004496291,0.00009258988,0.001843803,0.01733563,0.0001293214,0.002890927,0.00001912457],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963561,0.001048736,0.0004789752,0.0001492728,0.00003776406,0.0009725707,0.0003239583,0.00003581682,0.0005968312],"genre_scores_gemma":[0.9944283,0.001169895,0.001150381,0.0002772205,0.00006003884,0.0007723339,0.0008802506,0.00001284344,0.001248774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001694918,"threshold_uncertainty_score":0.006082892,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01879616199448288,"score_gpt":0.3007050673734482,"score_spread":0.2819089053789653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}