{"id":"W2597243443","doi":"10.1182/blood.v106.11.934.934","title":"A Phase II Study of Enzastaurin, a Protein Kinase C-β (PKCβ) Inhibitor, in the Treatment of Relapsed Diffuse Large B-Cell Lymphoma (DLBCL).","year":2005,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Medicine; Internal medicine; Phases of clinical research; Diffuse large B-cell lymphoma; Neutropenia; Febrile neutropenia; Transplantation; Progressive disease; Toxicity; Oncology; Pharmacology; Surgery; Chemotherapy; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004586697,0.0002665918,0.0005805184,0.0002469944,0.00007413368,0.000009524848,0.0002427495,0.0001096247,0.00003505007],"category_scores_gemma":[0.00009854385,0.0001697219,0.0001555716,0.0005196906,0.0000905437,0.00006158579,0.00009251577,0.0001161777,0.00001497524],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001970326,"about_ca_system_score_gemma":0.00213599,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009652594,"about_ca_topic_score_gemma":0.0005429247,"domain_scores_codex":[0.9974009,0.0002219419,0.0006753089,0.0003880258,0.0008116105,0.0005022128],"domain_scores_gemma":[0.9984745,0.0001106756,0.000181068,0.0009906573,0.0001039748,0.0001390784],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"nonrandomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.002228606,0.930258,0.0004771459,0.000260643,0.000223386,0.0009490223,0.02503172,0.000001395911,0.03254472,0.0000338993,0.0001572482,0.007834161],"study_design_scores_gemma":[0.7517664,0.03345165,0.0002422366,0.00015638,0.0004266517,0.00007059124,0.003337689,0.0004337571,0.2077658,0.000006889357,0.002191273,0.0001506393],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944259,0.00119247,0.000001561092,0.0001354318,0.00002055028,0.003656506,0.00002829355,0.00002714506,0.0005121382],"genre_scores_gemma":[0.9983945,0.00008299928,0.0001327649,0.00003937365,0.0001671675,0.0004450242,0.00001395645,0.00003679548,0.000687375],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8968064,"threshold_uncertainty_score":0.6921057,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01879616199448288,"score_gpt":0.3007050673734482,"score_spread":0.2819089053789653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}