{"id":"W2597266194","doi":"10.1200/jco.2013.31.15_suppl.2546","title":"Effects of gefitinib and vandetanib on human equilibrative nucleoside transporter 1 and on gemcitabine cytotoxicity.","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Vandetanib; Gemcitabine; Gefitinib; Pharmacology; Medicine; Cytidine; Tyrosine kinase; Tyrosine-kinase inhibitor; Nucleoside; Cancer research; Epidermal growth factor receptor; Chemistry; Internal medicine; Biochemistry; Cancer; Receptor; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001933584,0.0003007866,0.0004763971,0.0002087774,0.0001428091,0.0004072251,0.0002401487,0.0003922109,0.001289933],"category_scores_gemma":[0.0002238217,0.0001717259,0.0004100009,0.0002174625,0.0001892493,0.0002040416,0.0001127918,0.0003657516,0.0004341543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007391614,"about_ca_system_score_gemma":0.0003131572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003816957,"about_ca_topic_score_gemma":0.004528277,"domain_scores_codex":[0.999806,0.00004857789,0.00002156626,0.00003292554,0.00003841776,0.00005263524],"domain_scores_gemma":[0.999898,0.00003035519,0.00002304993,0.000009328951,0.00001875405,0.0000206757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003875636,0.0003965613,0.001929173,0.0001775925,0.00006889217,0.0001221133,0.0000524545,0.0007377575,0.9825659,0.0001437423,0.0004135817,0.009516703],"study_design_scores_gemma":[0.0002756394,0.005449377,0.02808676,0.00001422127,0.00008180297,0.0007491083,0.00007440421,0.002968558,0.956372,0.00004949512,0.005855454,0.0000232376],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900697,0.006301261,0.0002931091,0.0001063647,0.00004750795,0.00003276806,0.0007293735,0.00005815213,0.002361698],"genre_scores_gemma":[0.9951558,0.001422704,0.0005931718,0.00004493472,0.00001415745,0.00002713385,0.001168235,0.00001330817,0.001560572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003816957,"threshold_uncertainty_score":0.007589519,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04916109599232144,"score_gpt":0.3895318791729708,"score_spread":0.3403707831806494,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}