{"id":"W2597385024","doi":"10.1016/j.ynstr.2017.03.001","title":"Stress &amp; the gut-brain axis: Regulation by the microbiome","year":2017,"lang":"en","type":"review","venue":"Neurobiology of Stress","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1114,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Natural Sciences and Engineering Research Council of Canada; Joint Programming Initiative A healthy diet for a healthy life; Department of Agriculture, Food and the Marine, Ireland; National Institute of Mental Health; Ontario Brain Institute; National Institutes of Health; Science Foundation Ireland; Mead Johnson Nutrition","keywords":"Gut–brain axis; Gut flora; Irritable bowel syndrome; Anxiety; Microbiome; Physiology; Biology; Immune system; Neuroscience; Psychology; Medicine; Immunology; Bioinformatics; Internal medicine; Psychiatry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003852853,0.0005144192,0.001007256,0.00006850603,0.0004472466,0.00004804266,0.00171299,0.0008434104,0.00004442113],"category_scores_gemma":[0.0001202687,0.0002885938,0.0004852538,0.00009336251,0.0009293116,0.000004047018,0.0004535103,0.0005249158,0.00003698601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001893375,"about_ca_system_score_gemma":0.0002456289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006700472,"about_ca_topic_score_gemma":0.0001594959,"domain_scores_codex":[0.9972718,0.000734036,0.0007044541,0.0007201437,0.00008278045,0.0004867434],"domain_scores_gemma":[0.9966192,0.0001627504,0.001143055,0.001905737,0.0001053477,0.00006388623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008224697,0.0003116497,0.0001293521,0.00967177,0.0008619359,0.000003070224,0.0001346785,0.000006625811,0.1473443,0.0001377895,0.4404356,0.4008809],"study_design_scores_gemma":[0.0001883835,0.0001219879,0.0001570647,0.0009181627,0.000167539,0.0000616769,0.00001019974,1.077743e-7,0.001233301,0.000007294641,0.9968717,0.0002625918],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002468784,0.9918648,0.00001477421,0.0009401416,0.0007097194,0.0009951225,0.002627588,0.00001423246,0.0003648435],"genre_scores_gemma":[0.0009105055,0.988508,0.00002247567,0.0003659782,0.0004098677,0.00006820214,0.004903753,0.0000678843,0.004743292],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5564361,"threshold_uncertainty_score":0.9999566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05453887342697585,"score_gpt":0.3552460926673405,"score_spread":0.3007072192403646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}