{"id":"W2597428467","doi":"10.1038/nature21725","title":"Complex pectin metabolism by gut bacteria reveals novel catalytic functions","year":2017,"lang":"en","type":"article","venue":"Nature","topic":"Polysaccharides and Plant Cell Walls","field":"Agricultural and Biological Sciences","cited_by":631,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lethbridge College","funders":"Basic Energy Sciences; Biotechnology and Biological Sciences Research Council; Agence Nationale de la Recherche; European Commission; U.S. Department of Energy; Diamond Light Source; Wellcome Trust","keywords":"Bacteroides thetaiotaomicron; Glycan; Bacteria; Glycosyltransferase; Biochemistry; Glycoside hydrolase; Enzyme; Glycobiology; Glycosidic bond; Microbiome; Bacteroides; Microbial metabolism; Polysaccharide; Metabolism; Pectin; Biology; Chemistry; Microbiology; Glycoprotein; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001621146,0.0002958223,0.0001760817,0.0001229347,0.0001217826,0.0005474245,0.0001562445,0.0004760519,0.0006126661],"category_scores_gemma":[0.0001335472,0.0001545211,0.0001682146,0.0001367725,0.0002334738,0.0003706669,0.0002930435,0.0003295904,0.0001684499],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001617846,"about_ca_system_score_gemma":0.00009761678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000236051,"about_ca_topic_score_gemma":0.0003343717,"domain_scores_codex":[0.9999328,0.000008937905,0.000002689977,0.00001623084,0.00001572844,0.00002357368],"domain_scores_gemma":[0.9999398,0.00001229789,0.00001137998,0.00001181558,0.000006595323,0.00001820227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001676973,0.00001827935,0.001834122,0.00002409191,0.000008787289,0.00009733198,0.00002910732,0.00009042572,0.9940554,0.0003791537,0.00003163597,0.003264043],"study_design_scores_gemma":[0.000035667,0.0003275438,0.07234558,0.00001195916,0.00003871107,0.0009306769,0.0001856185,0.005604672,0.9174545,0.001073655,0.001977277,0.00001409858],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974813,0.0004870407,0.001409957,0.00005536781,0.000004716278,0.00000233118,0.00003446867,0.00001473794,0.0005101177],"genre_scores_gemma":[0.9981749,0.0001814063,0.001010871,0.00002105766,0.000003411972,0.000002208014,0.00009909766,0.000004812936,0.0005023085],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006126661,"threshold_uncertainty_score":0.002049625,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02548491159398728,"score_gpt":0.2444201579019105,"score_spread":0.2189352463079232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}