{"id":"W2597593796","doi":"10.1200/jco.2017.35.4_suppl.358","title":"Interim results of a multicenter phase II trial of <i>nab</i>-paclitaxel (<i>nab</i>-P) plus gemcitabine (G) for patients (Pts) with locally advanced pancreatic cancer (LAPC).","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Baker Hughes (Canada)","funders":"","keywords":"Medicine; Gemcitabine; Neutropenia; Internal medicine; Discontinuation; Interim analysis; Adverse effect; Gastroenterology; Clinical endpoint; Phases of clinical research; Febrile neutropenia; Surgery; Cancer; Clinical trial; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004946277,0.001381748,0.001323257,0.0003328317,0.0005608805,0.001254522,0.0008433621,0.001370968,0.003930937],"category_scores_gemma":[0.002669209,0.0004626589,0.001589432,0.0002952306,0.0007434312,0.0009682315,0.00049584,0.003024205,0.0008681882],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007119224,"about_ca_system_score_gemma":0.001769304,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006818323,"about_ca_topic_score_gemma":0.001797303,"domain_scores_codex":[0.9990964,0.0005226255,0.00004936714,0.00009692553,0.00006103725,0.0001737975],"domain_scores_gemma":[0.9976891,0.0005263632,0.0005457968,0.0001801994,0.0001445117,0.0009139985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8717475,0.02962618,0.007161309,0.000620259,0.002256752,0.0003182869,0.0002563586,0.002922345,0.01616678,0.0003344673,0.01844119,0.05014861],"study_design_scores_gemma":[0.5801007,0.3869599,0.01876557,0.00006720255,0.001748176,0.000363112,0.00005882522,0.001320252,0.00411169,0.0005103311,0.005951075,0.00004303556],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9604543,0.004575161,0.0023553,0.002837422,0.0007093622,0.00835027,0.01084166,0.0003091609,0.009567363],"genre_scores_gemma":[0.9584052,0.001605486,0.005043925,0.002982304,0.0003758405,0.008968948,0.01730592,0.0001074487,0.005204937],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004946277,"threshold_uncertainty_score":0.02615875,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1414387291662786,"score_gpt":0.5281105214175,"score_spread":0.3866717922512214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}