{"id":"W2597968140","doi":"10.1182/blood.v128.22.5193.5193","title":"In Vitro Comparison of ADCC and CAR Sensitivity of Adult HER-2+ B-ALL Using the NK-92 Human Cell Line Transduced with a Human CD16 (ADCC) or an Anti-HER2 Chimeric Antigen Receptor (CAR)","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"","keywords":"Antibody-dependent cell-mediated cytotoxicity; Cytotoxic T cell; Medicine; Chimeric antigen receptor; CD20; Immunology; Antigen; Antibody; Cancer research; Monoclonal antibody; In vitro; Biology; Immunotherapy; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004990411,0.0004670651,0.0003458978,0.0002629905,0.0001692929,0.0003336262,0.0002129539,0.0002739086,0.002194579],"category_scores_gemma":[0.0002122564,0.000202205,0.0002926239,0.0003713909,0.0001536321,0.0001994009,0.0002040231,0.0004686824,0.0005048831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002325917,"about_ca_system_score_gemma":0.000170155,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00146048,"about_ca_topic_score_gemma":0.001095725,"domain_scores_codex":[0.9994689,0.0001969859,0.00009405396,0.00006603426,0.0001098282,0.00006423748],"domain_scores_gemma":[0.9997463,0.0001036285,0.00001825882,0.00005557414,0.00004756764,0.00002876913],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007838852,0.0003685273,0.0009895317,0.000188421,0.00003993099,0.00008093867,0.00009647485,0.0003512297,0.9928437,0.0001443478,0.0001336093,0.003979405],"study_design_scores_gemma":[0.0001165417,0.003812353,0.008339485,0.00002037369,0.00007700588,0.0003705412,0.00006410874,0.002347007,0.9826283,0.00005006564,0.002162161,0.00001196185],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914517,0.003896856,0.001731961,0.00003980908,0.0000458969,0.00005669165,0.0005520699,0.00003953225,0.002185544],"genre_scores_gemma":[0.9900584,0.002135612,0.002328566,0.00003327976,0.00002630789,0.00007389377,0.002532761,0.0000101111,0.002801141],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002194579,"threshold_uncertainty_score":0.007341623,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04747231502687925,"score_gpt":0.3411046266775939,"score_spread":0.2936323116507147,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}