{"id":"W2598131512","doi":"10.1128/mcb.00089-17","title":"Endothelial NO Synthase-Dependent S-Nitrosylation of <i>β</i> -Catenin Prevents Its Association with TCF4 and Inhibits Proliferation of Endothelial Cells Stimulated by Wnt3a","year":2017,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Université de Montréal; Chinese Academy of Sciences; Government of Canada","keywords":"Biology; WNT3A; Catenin; Beta-catenin; TCF4; Cell biology; Cancer research; Wnt signaling pathway; Signal transduction; Genetics; Transcription factor; Gene; Enhancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001803524,0.0002719985,0.000245074,0.000139795,0.0001406998,0.0001999179,0.0001881177,0.0001504349,0.001235971],"category_scores_gemma":[0.0001293172,0.0001369294,0.0002986154,0.0001179392,0.0002066649,0.0001244897,0.0001274426,0.0004358329,0.0002296094],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002727687,"about_ca_system_score_gemma":0.0002587079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000967044,"about_ca_topic_score_gemma":0.001629434,"domain_scores_codex":[0.9998522,0.00002820575,0.00001875401,0.00002901674,0.00003877688,0.00003310389],"domain_scores_gemma":[0.9999166,0.000009313141,0.00002929167,0.000009230792,0.00001035645,0.00002520048],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009755444,0.00002935763,0.0001073267,0.00002622326,0.0000051901,0.00001321207,0.000006367066,0.00002277281,0.999081,0.00005051115,0.00002414324,0.000536262],"study_design_scores_gemma":[0.00001873288,0.0001604599,0.002863255,0.00000439021,0.00000923169,0.00009947897,0.000007946467,0.0005859288,0.9945661,0.0000250919,0.001656873,0.000002463838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937643,0.002218325,0.002263043,0.00009470181,0.00004975537,0.00003030838,0.0001881274,0.0000529372,0.001338429],"genre_scores_gemma":[0.9940974,0.0009444827,0.001543145,0.00005226827,0.00001120066,0.00004399684,0.000653335,0.00001356263,0.002640509],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001235971,"threshold_uncertainty_score":0.004134715,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005292101892442108,"score_gpt":0.2166082212913356,"score_spread":0.2113161193988935,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}