{"id":"W2598773960","doi":"10.1177/1010428317692248","title":"Proteasome expression and activity in cancer and cancer stem cells","year":2017,"lang":"en","type":"review","venue":"Tumor Biology","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"NOSM University; Sault Area Hospital","funders":"","keywords":"Proteasome; Cancer stem cell; Cancer; Cancer cell; Biology; Proteostasis; Cell biology; Stem cell; Carcinogenesis; Cancer research; Regulator; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003829041,0.0007124508,0.0009971461,0.00225586,0.0002997181,0.0009169753,0.0006433201,0.001028977,0.001803647],"category_scores_gemma":[0.0004597477,0.0002556749,0.0003506269,0.001986193,0.0005568715,0.001264422,0.0006760348,0.001535627,0.001244715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007543248,"about_ca_system_score_gemma":0.0007936486,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008587921,"about_ca_topic_score_gemma":0.001396428,"domain_scores_codex":[0.9998468,0.0000203773,0.00002472135,0.00003069202,0.00006055344,0.00001684787],"domain_scores_gemma":[0.9998473,0.00005767537,0.00002563694,0.000005785504,0.00004495117,0.00001864514],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000733912,0.00004489627,0.0002744306,0.01149691,0.00005832921,0.0003439514,0.00006951568,0.0003678556,0.003338983,0.006176447,0.02129791,0.9564573],"study_design_scores_gemma":[0.000008977197,0.00006553603,0.001094711,0.001896427,0.00005932516,0.002052617,0.00005046071,0.00008178249,0.001087664,0.002990547,0.9905929,0.00001919634],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001094093,0.9988534,0.00008114937,0.0001475005,0.0001191745,0.000001769643,0.000009751525,0.000004032352,0.0006737327],"genre_scores_gemma":[0.0008119861,0.9983554,0.0001029762,0.0001087997,0.0001237556,0.000003666607,0.00002262442,0.000001076717,0.0004696066],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00225586,"threshold_uncertainty_score":0.006033778,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07803533344112414,"score_gpt":0.3666395713905636,"score_spread":0.2886042379494395,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}