{"id":"W2599537025","doi":"10.3389/fonc.2017.00050","title":"Update on the Treatment of Metastatic Squamous Non-Small Cell Lung Cancer in New Era of Personalized Medicine","year":2017,"lang":"en","type":"review","venue":"Frontiers in Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Epidermal growth factor receptor; Epithelial–mesenchymal transition; Medicine; Lung cancer; Cancer research; Discoidin domain; Personalized medicine; Tyrosine kinase; Oncology; Targeted therapy; Precision medicine; Lung; Cancer; Receptor tyrosine kinase; Internal medicine; Bioinformatics; Pathology; Receptor; Biology; Metastasis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002180844,0.0003838938,0.003389893,0.0003571606,0.00004163139,0.000002994757,0.0002346678,0.0002163264,0.0002982926],"category_scores_gemma":[0.00006511589,0.000207854,0.0003357916,0.0002222051,0.0002866215,0.00001920634,0.00001889189,0.0003106715,0.000003059002],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002094357,"about_ca_system_score_gemma":0.003859234,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002862125,"about_ca_topic_score_gemma":0.0008473785,"domain_scores_codex":[0.9981027,0.000222187,0.0008366128,0.0003692072,0.0001818552,0.0002874144],"domain_scores_gemma":[0.9980512,0.0003395987,0.0008952057,0.0005585452,0.00005424091,0.0001012683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002183209,0.001007255,0.001060769,0.004559882,0.001114829,0.0001891314,0.003578797,0.00000908837,5.521488e-7,0.00006872442,0.01441759,0.9737751],"study_design_scores_gemma":[0.007977417,0.002374376,0.0001506016,0.007879982,0.007450557,0.00001136642,0.0003782309,0.00005185337,0.000004350063,0.00004674065,0.9735315,0.000143066],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002177478,0.9898887,0.00008919639,0.001447521,0.00115457,0.002857698,0.0001193347,0.000005389846,0.004219892],"genre_scores_gemma":[0.0001779652,0.9932927,0.001628615,0.000129744,0.0001544135,0.0005496335,0.0001239958,0.00004279331,0.003900144],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.973632,"threshold_uncertainty_score":0.8476042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06153199649100901,"score_gpt":0.4331107286308508,"score_spread":0.3715787321398418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}