{"id":"W2599739225","doi":"10.7554/elife.20851","title":"Age-dependent diastolic heart failure in an in vivo Drosophila model","year":2017,"lang":"en","type":"article","venue":"eLife","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; Heart and Stroke Foundation of Canada; Jane Coffin Childs Memorial Fund for Medical Research; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Howard Hughes Medical Institute","keywords":"Heartbeat; Cardiac cycle; Diastole; Drosophila melanogaster; Heart failure; Contraction (grammar); Homeostasis; Pulsatile flow; Internal medicine; In vivo; Cardiac function curve; Biology; Cardiology; Neuroscience; Cell biology; Medicine; Computer science; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003758959,0.0005938867,0.0002555962,0.0006797331,0.0003803692,0.0003295449,0.0005935237,0.0007677521,0.002405599],"category_scores_gemma":[0.0001994637,0.0003338283,0.0003410006,0.000165141,0.0004271059,0.0003244835,0.000392924,0.0009396708,0.0005816588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006328,"about_ca_system_score_gemma":0.0002704964,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001688846,"about_ca_topic_score_gemma":0.003226014,"domain_scores_codex":[0.9998345,0.00002215653,0.00001901561,0.0000618253,0.00003987822,0.00002250858],"domain_scores_gemma":[0.9997726,0.00003201404,0.0000752313,0.00003559078,0.00002115879,0.00006342032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000156382,0.00008897226,0.0005130012,0.00005638177,0.00001092483,0.000231691,0.00005353434,0.0003593777,0.9962065,0.0006590566,0.0002645333,0.001399613],"study_design_scores_gemma":[0.0003800878,0.002383794,0.02059668,0.0001008641,0.000138707,0.002973838,0.0002904939,0.01718023,0.9309258,0.001116651,0.02384529,0.00006753929],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9704958,0.001770403,0.01742347,0.0004733019,0.0001363701,0.0002749277,0.004752077,0.0002804272,0.004393249],"genre_scores_gemma":[0.9625862,0.002135825,0.01963668,0.0003260423,0.00003205526,0.0005239255,0.002867661,0.0001203528,0.01177115],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002405599,"threshold_uncertainty_score":0.008047581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03097367055668689,"score_gpt":0.2652489154820599,"score_spread":0.234275244925373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}