{"id":"W2600014321","doi":"10.1200/jco.2013.31.15_suppl.5009","title":"Long-term safety and efficacy analysis of abiraterone acetate (AA) plus prednisone (P) in metastatic castration-resistant prostate cancer (mCRPC) without prior chemotherapy (COU-AA-302).","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Medicine; Abiraterone acetate; Tolerability; Prostate cancer; Internal medicine; Interim analysis; Post-hoc analysis; Urology; Placebo; Adverse effect; Prednisone; Chemotherapy; Incidence (geometry); Oncology; Gastroenterology; Cancer; Randomized controlled trial; Androgen deprivation therapy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00247103,0.0006666772,0.001067613,0.0004223464,0.0002456778,0.0007044721,0.0004737586,0.0005924126,0.002187652],"category_scores_gemma":[0.00172021,0.000308959,0.001562959,0.0004070148,0.0006911837,0.0005341863,0.0003339534,0.001770274,0.0004911588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006529873,"about_ca_system_score_gemma":0.0009986812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004823499,"about_ca_topic_score_gemma":0.001492619,"domain_scores_codex":[0.9991527,0.0004753897,0.0000619436,0.00009956938,0.0001097797,0.000100586],"domain_scores_gemma":[0.9983729,0.0003915712,0.0005318953,0.0001564439,0.0000804673,0.0004666949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8982765,0.02148472,0.01191614,0.000476566,0.002229427,0.000138138,0.000151831,0.00110494,0.0150369,0.00008257154,0.0005815579,0.04852068],"study_design_scores_gemma":[0.1733395,0.7652277,0.05146247,0.00004989203,0.002421203,0.0003485735,0.00007908628,0.001009927,0.004254746,0.0001880718,0.001584659,0.0000341556],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973543,0.001226917,0.0002646123,0.00008247423,0.00003239337,0.0002614889,0.0003324717,0.0000196512,0.0004258022],"genre_scores_gemma":[0.9978387,0.0005658385,0.000329453,0.0001065845,0.00007410852,0.0001507124,0.0004647517,0.00000582997,0.0004640081],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00247103,"threshold_uncertainty_score":0.0130682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1037629780267593,"score_gpt":0.4775222899404867,"score_spread":0.3737593119137274,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}