{"id":"W2600737182","doi":"10.1182/blood.v120.21.137.137","title":"Continuous Dose Dasatinib Is Safe and Feasible in Combination with Intensive Chemotherapy in Pediatric Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL): Children's Oncology Group (COG) Trial AALL0622","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital","funders":"","keywords":"Dasatinib; Medicine; Cohort; Internal medicine; Imatinib; Acute lymphocytic leukemia; Chemotherapy; Oncology; Clinical endpoint; Surgery; Clinical trial; Leukemia; Lymphoblastic Leukemia; Myeloid leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001255476,0.0007159639,0.001105324,0.0002553875,0.0002924925,0.001165688,0.0007347591,0.0008253024,0.002089162],"category_scores_gemma":[0.0006930715,0.0002912518,0.0008832146,0.0003381943,0.0006190989,0.0005430865,0.0004280821,0.002077532,0.0004704655],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007617089,"about_ca_system_score_gemma":0.001270963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009413513,"about_ca_topic_score_gemma":0.003137853,"domain_scores_codex":[0.9994136,0.0003575956,0.00003017131,0.00006668623,0.00005975276,0.00007211917],"domain_scores_gemma":[0.9993634,0.00008307022,0.0001603205,0.00005616359,0.00002588163,0.000311224],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.793685,0.0325867,0.01937588,0.0007160453,0.001400487,0.0004195266,0.0003264324,0.00440446,0.02970329,0.0006983724,0.007493132,0.1091907],"study_design_scores_gemma":[0.5645348,0.3941351,0.02434169,0.00008325311,0.0005790176,0.0005540998,0.00008978547,0.001898568,0.005050344,0.0004147188,0.008272017,0.0000465285],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959983,0.001112265,0.0001526787,0.0003079968,0.00004526182,0.0005100122,0.0006032049,0.00004843817,0.00122202],"genre_scores_gemma":[0.9952499,0.0009528568,0.0006940919,0.0004653584,0.00009949013,0.0007763645,0.001021751,0.00001317227,0.0007270762],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002089162,"threshold_uncertainty_score":0.006989002,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01242245507725019,"score_gpt":0.2694340915628597,"score_spread":0.2570116364856095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}