{"id":"W2600797084","doi":"10.1200/jco.2013.31.15_suppl.2023","title":"Biomarker (BM) evaluations in the phase III AVAglio study of bevacizumab (Bv) plus standard radiotherapy (RT) and temozolomide (T) for newly diagnosed glioblastoma (GBM).","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Bevacizumab; Internal medicine; Temozolomide; Oncology; Progression-free survival; Placebo; Radiation therapy; Gastroenterology; Overall survival; Chemotherapy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003451681,0.00085444,0.001274871,0.0002706347,0.0001830712,0.000698455,0.0005266932,0.000654174,0.001758409],"category_scores_gemma":[0.001740235,0.0003377647,0.0007389129,0.0003464915,0.0003278886,0.0005226182,0.0003674126,0.001415075,0.0004941706],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006266867,"about_ca_system_score_gemma":0.001041644,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006412232,"about_ca_topic_score_gemma":0.001116154,"domain_scores_codex":[0.9990684,0.0006396443,0.00003229148,0.00009908625,0.00008501946,0.00007556236],"domain_scores_gemma":[0.9991881,0.000184227,0.0002726954,0.0000451732,0.00006583583,0.00024391],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.852575,0.01302808,0.02700279,0.0005867288,0.00191684,0.00006489995,0.0001469613,0.001217465,0.0259274,0.0001782032,0.001763651,0.07559205],"study_design_scores_gemma":[0.2581082,0.6306469,0.09491272,0.00004956688,0.002339543,0.0002485795,0.00005767097,0.002356055,0.007007859,0.000314876,0.003920873,0.00003720266],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948229,0.002028726,0.0004146291,0.0002280366,0.00004596323,0.0008601303,0.0006752908,0.00005462112,0.0008697693],"genre_scores_gemma":[0.9952587,0.0006756067,0.001004103,0.0003332175,0.00007623027,0.0009089664,0.001041336,0.00001469516,0.0006870363],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003451681,"threshold_uncertainty_score":0.0182544,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1157911030521943,"score_gpt":0.4956195926768929,"score_spread":0.3798284896246986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}