{"id":"W2601049681","doi":"10.1182/blood.v110.11.1417.1417","title":"Histone Deacetylase Inhibitor Valproic Acid Has Differential Effects on Trafficking of Normal Hematopoietic Stem/Progenitor Cells and Leukemic Blasts.","year":2007,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services; University of Alberta","funders":"","keywords":"Cancer research; Haematopoiesis; Progenitor cell; Bone marrow; Stem cell; CD34; Leukemia; Biology; Myeloid; CXCR4; Myeloid leukemia; Stromal cell; Homing (biology); Myelopoiesis; Stem cell factor; Immunology; Cell biology; Chemokine; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001125403,0.0002416419,0.0002853723,0.0001828132,0.0001234958,0.0002155187,0.0001613229,0.0001720726,0.00125326],"category_scores_gemma":[0.00008958054,0.0001231374,0.0002636176,0.0001809042,0.0001712262,0.0001259683,0.00009082534,0.0004091363,0.0003122911],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002802422,"about_ca_system_score_gemma":0.0001898453,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008780864,"about_ca_topic_score_gemma":0.000926316,"domain_scores_codex":[0.9998825,0.00002223269,0.00001145617,0.0000266158,0.00002555765,0.00003169056],"domain_scores_gemma":[0.9999361,0.00001341365,0.00001158923,0.000008561428,0.000007675023,0.00002272439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007855222,0.0000970651,0.0001661147,0.00004009706,0.000009393201,0.00003791646,0.00001354103,0.00007400454,0.9955173,0.00007071692,0.0001040429,0.003084221],"study_design_scores_gemma":[0.00008512743,0.001114882,0.003417795,0.000003728688,0.00001985256,0.0001281156,0.00001892985,0.0007644711,0.9926974,0.00002790549,0.001718672,0.00000307145],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940672,0.002923933,0.0006299159,0.00008805442,0.00005989125,0.00002823671,0.0005745033,0.00009448311,0.001533726],"genre_scores_gemma":[0.9952902,0.001176983,0.0009603287,0.00006684476,0.00001079884,0.00003397742,0.0009068283,0.00002370509,0.001530347],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00125326,"threshold_uncertainty_score":0.004192531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01361711410927053,"score_gpt":0.2601441598105263,"score_spread":0.2465270457012558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}