{"id":"W2601263990","doi":"10.1116/1.4978871","title":"Bioavailability of immobilized epidermal growth factor: Covalent versus noncovalent grafting","year":2017,"lang":"en","type":"article","venue":"Biointerphases","topic":"Silk-based biomaterials and applications","field":"Materials Science","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"École de Technologie Supérieure; Centre Hospitalier de l’Université de Montréal; National Research Council Canada; Polytechnique Montréal","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Covalent bond; Epidermal growth factor; Chondroitin sulfate; Chemistry; Biophysics; Cysteine; Peptide; Coiled coil; Biochemistry; Glycosaminoglycan; Enzyme; Receptor; Organic chemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004123802,0.0002220526,0.000383216,0.00005561776,0.0003912585,0.0002205369,0.0007148686,0.00007653241,0.001719299],"category_scores_gemma":[0.000509341,0.0001803074,0.0001948016,0.00004138122,0.0005937744,0.0002333525,0.0002612914,0.00004171842,0.0002434646],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006364136,"about_ca_system_score_gemma":0.00007692149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009682604,"about_ca_topic_score_gemma":0.0000478695,"domain_scores_codex":[0.9982545,0.00008701361,0.0005827749,0.0004847604,0.0002571281,0.0003338131],"domain_scores_gemma":[0.9978772,0.0002243705,0.0005615712,0.001049428,0.0001702746,0.0001171589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003839859,0.0002843372,0.004176523,0.00007478118,0.00001641078,0.000003457517,0.00005326175,3.965019e-7,0.9935777,0.0003495552,0.0002871236,0.000792518],"study_design_scores_gemma":[0.001603507,0.0002375147,0.01419011,0.00006653622,0.00003216084,0.000004299715,0.00005481535,0.00002988608,0.9826148,0.00008403326,0.0008761773,0.0002062236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996332,0.0001231742,0.0003241552,0.0003032689,0.001225003,0.00035851,0.0007050517,0.000102429,0.0005264106],"genre_scores_gemma":[0.9977722,0.0000241788,0.001897733,0.00003012519,0.0001531704,0.00005117554,0.00001788778,0.0000174778,0.00003603849],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01096291,"threshold_uncertainty_score":0.9991933,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05544086506712871,"score_gpt":0.3286054232939662,"score_spread":0.2731645582268375,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}