{"id":"W2601263990","doi":"10.1116/1.4978871","title":"Bioavailability of immobilized epidermal growth factor: Covalent versus noncovalent grafting","year":2017,"lang":"en","type":"article","venue":"Biointerphases","topic":"Silk-based biomaterials and applications","field":"Materials Science","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"École de Technologie Supérieure; Centre Hospitalier de l’Université de Montréal; National Research Council Canada; Polytechnique Montréal","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Covalent bond; Epidermal growth factor; Chondroitin sulfate; Chemistry; Biophysics; Cysteine; Peptide; Coiled coil; Biochemistry; Glycosaminoglycan; Enzyme; Receptor; Organic chemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003455295,0.000391829,0.0001688626,0.0001531787,0.0001279655,0.0004574266,0.0002741931,0.0003044591,0.0008569378],"category_scores_gemma":[0.0003624263,0.0001215191,0.0002022426,0.0001266499,0.0002143077,0.0002745423,0.0002343518,0.0003004911,0.0002069903],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003120858,"about_ca_system_score_gemma":0.0001666105,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000581505,"about_ca_topic_score_gemma":0.0008267754,"domain_scores_codex":[0.9997762,0.00003717735,0.0000168024,0.00005869515,0.00007029816,0.00004087786],"domain_scores_gemma":[0.9998184,0.00007131436,0.00004474697,0.00002060394,0.00002929656,0.00001567619],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005392926,0.00002020551,0.0001321755,0.00003960886,0.000006163424,0.00001444907,0.000009397805,0.00008895962,0.9974319,0.00007101006,0.000008725108,0.002123391],"study_design_scores_gemma":[0.00000326265,0.00009430233,0.0004008749,0.00000186355,0.00001066636,0.00002824732,0.000006552631,0.0003881811,0.9986984,0.00001152522,0.000354189,0.000002024367],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891289,0.001831844,0.007883093,0.00004946282,0.00002198711,0.00003199074,0.00004172789,0.00003990127,0.0009711867],"genre_scores_gemma":[0.9943234,0.0007339312,0.003813476,0.00002968618,0.00001021378,0.00001344841,0.00006348114,0.00001555276,0.0009968868],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008569378,"threshold_uncertainty_score":0.002866745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05544086506712871,"score_gpt":0.3286054232939662,"score_spread":0.2731645582268375,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}