{"id":"W2601584465","doi":"10.1161/atvb.32.suppl_1.a362","title":"Abstract 362: Akt-Dependent Interaction with EBP50 Regulates Skp2 Localization and Stability","year":2012,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Barrick Gold (Canada)","funders":"","keywords":"Protein kinase B; SKP2; Phosphorylation; Biology; Cell biology; PDZ domain; Immunoprecipitation; Ezrin; PI3K/AKT/mTOR pathway; Ubiquitin ligase; Signal transduction; Biochemistry; Ubiquitin; Cell; Cytoskeleton","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009489788,0.0004196837,0.0001932406,0.0001616256,0.0002366765,0.0002656927,0.0001721684,0.0002264549,0.004345209],"category_scores_gemma":[0.00009807602,0.0001573141,0.0002542783,0.0001349554,0.0002572656,0.0001729402,0.000288058,0.0003863865,0.001849292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004974654,"about_ca_system_score_gemma":0.0002150655,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006187526,"about_ca_topic_score_gemma":0.0008221317,"domain_scores_codex":[0.9998938,0.00001384256,0.000009305267,0.00003176424,0.00002502503,0.00002631414],"domain_scores_gemma":[0.999944,0.000006601782,0.00001537521,0.000006636443,0.00000488472,0.00002248139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002714214,0.00002682676,0.0002376317,0.00003941026,0.000005262821,0.00007538639,0.000007391711,0.00004535444,0.9983087,0.00008526649,0.0001351144,0.0007622369],"study_design_scores_gemma":[0.00006576074,0.0001446385,0.02174501,0.00001216793,0.0000181651,0.0003193053,0.00002178411,0.001452897,0.9727905,0.0001055594,0.003316872,0.000007270866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935067,0.001590306,0.001349475,0.000163539,0.00004243062,0.00001593046,0.0007847738,0.0001013754,0.002445511],"genre_scores_gemma":[0.990502,0.0006499083,0.0009276431,0.0001133139,0.00001779055,0.00003777523,0.001734379,0.00003627099,0.005980886],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004345209,"threshold_uncertainty_score":0.01453614,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03240585861297324,"score_gpt":0.266342089881675,"score_spread":0.2339362312687017,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}