{"id":"W2601643262","doi":"","title":"Investigation of the effect mutations of CaM have upon in vitro and ex vivo function","year":2010,"lang":"en","type":"dissertation","venue":"UWSpace (University of Waterloo)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Waterloo","keywords":"Ex vivo; In vitro; In vivo; Function (biology); Biology; Computational biology; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001214881,0.0001154347,0.0001789176,0.00009103966,0.00004491975,0.000002909754,0.0001432242,0.0002848223,0.000009178196],"category_scores_gemma":[0.00005153368,0.0001144713,0.00009473332,0.00008053535,0.000129264,0.00000641397,0.00004172279,0.000126381,4.307084e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001104298,"about_ca_system_score_gemma":0.00007158201,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004133686,"about_ca_topic_score_gemma":0.01474673,"domain_scores_codex":[0.9994004,0.00009152068,0.0001050627,0.0001966235,0.0001247409,0.00008160533],"domain_scores_gemma":[0.9993402,0.00002072372,0.0002684684,0.0002316725,0.0001039269,0.00003505556],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004543731,0.00001239122,0.007587543,0.0002477133,0.00003977058,5.948271e-7,0.005114503,0.00004108451,0.9861624,0.000004522255,0.00005899309,0.0002760909],"study_design_scores_gemma":[0.0005521773,0.0001688671,0.02583666,0.00009427788,0.0001415847,5.603656e-7,0.006094711,0.00006548876,0.9668803,0.00005074802,0.00001960421,0.00009499778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993402,0.00009511494,0.000006135208,0.00003933447,0.0001491169,0.0002442465,0.00006740481,0.000004204561,0.0000542879],"genre_scores_gemma":[0.9931365,0.0000106694,0.0001351123,0.000003643222,0.0000155305,7.302269e-7,0.0005902757,0.00001102768,0.006096477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0192821,"threshold_uncertainty_score":0.822902,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005408249114234969,"score_gpt":0.1887029165515763,"score_spread":0.1832946674373414,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}