{"id":"W2602128891","doi":"10.1038/srep45424","title":"Towards a Humanized Mouse Model of Liver Stage Malaria Using Ectopic Artificial Livers","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Liver physiology and pathology","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; National Cancer Institute; Agency for Science, Technology and Research; Howard Hughes Medical Institute; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology; Johns Hopkins University; Bill and Melinda Gates Foundation; Johns Hopkins Bloomberg School of Public Health; York University","keywords":"Malaria; Humanized mouse; Human liver; Animal model; In vivo; Biology; Medicine; Immunology; Biotechnology; In vitro; Internal medicine; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007671208,0.0001298864,0.0003603804,0.000135811,0.0005928345,0.00006627405,0.0001613544,0.0001475954,0.0003250681],"category_scores_gemma":[0.0002172465,0.0001135985,0.0001422442,0.00005871454,0.0008280943,0.0001787484,0.0001646715,0.0001597193,0.00001611448],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003810291,"about_ca_system_score_gemma":0.0003593772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002240211,"about_ca_topic_score_gemma":0.0000328469,"domain_scores_codex":[0.9984816,0.00004399363,0.0003959927,0.0005431875,0.0002727783,0.0002624127],"domain_scores_gemma":[0.9977593,0.00001099887,0.0005167714,0.001391075,0.000223444,0.00009834734],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001112365,0.0001562844,0.006204017,0.0000838933,0.00005261035,0.0008961738,0.0009808871,0.0003397539,0.9892582,0.001268431,0.0002549317,0.0003935274],"study_design_scores_gemma":[0.001342449,0.0002937424,0.04548326,0.0001494375,0.0005117386,0.0005708289,0.0001805431,0.06773362,0.864654,0.01786757,0.0006781431,0.0005346769],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994592,0.00002773299,0.000540507,0.00005054559,0.002043881,0.00028361,0.000009907923,0.00003190374,0.002419951],"genre_scores_gemma":[0.9868784,0.000003095031,0.00262447,0.00003217611,0.00008877205,0.000003585196,0.00002098235,0.00001253275,0.01033597],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1246043,"threshold_uncertainty_score":0.4632411,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1029108644654677,"score_gpt":0.3257293876093223,"score_spread":0.2228185231438546,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}