{"id":"W2602523427","doi":"10.1172/jci.insight.91166","title":"Store-operated Ca2+ entry controls ameloblast cell function and enamel development","year":2017,"lang":"en","type":"article","venue":"JCI Insight","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Dental and Craniofacial Research; National Institute of Allergy and Infectious Diseases; Deutsche Forschungsgemeinschaft; York University; New York University Abu Dhabi","keywords":"Ameloblast; Cell biology; Enamel paint; Chemistry; ORAI1; Calbindin; STIM1; Endocrinology; Biology; Internal medicine; Calcium; Endoplasmic reticulum; Medicine; Dentistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001338871,0.00033844,0.0002222105,0.0005128916,0.0002236246,0.0005035717,0.000216059,0.0003259848,0.001026347],"category_scores_gemma":[0.0001635082,0.0002326855,0.00009852916,0.0001705659,0.0003608894,0.0003279152,0.0003969277,0.0003248398,0.0002579434],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004469039,"about_ca_system_score_gemma":0.0003338862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001082473,"about_ca_topic_score_gemma":0.001985523,"domain_scores_codex":[0.9998518,0.00001513807,0.00001131835,0.00003236319,0.00004859036,0.00004073858],"domain_scores_gemma":[0.9998135,0.00001844677,0.00006813409,0.00001679121,0.00002905413,0.00005406318],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006006876,0.000004976169,0.0005983732,0.00001996348,0.000002069856,0.00007932192,0.0000211423,0.00005236473,0.99743,0.0002328206,0.0000565418,0.00144234],"study_design_scores_gemma":[0.00002526647,0.0001064804,0.07169484,0.00001659788,0.00002304161,0.0007489939,0.0001755223,0.002999313,0.9169891,0.0005433614,0.006662964,0.00001448826],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915034,0.002954317,0.002347874,0.0001639168,0.00002108296,0.00001240401,0.0003147341,0.000184011,0.002498311],"genre_scores_gemma":[0.9948644,0.001560577,0.0009923242,0.00002456635,0.000009822441,0.0000139322,0.0001336473,0.00003643109,0.00236434],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001082473,"threshold_uncertainty_score":0.003433526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008958699687272186,"score_gpt":0.2168575878924131,"score_spread":0.2078988882051409,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}