{"id":"W2602523427","doi":"10.1172/jci.insight.91166","title":"Store-operated Ca2+ entry controls ameloblast cell function and enamel development","year":2017,"lang":"en","type":"article","venue":"JCI Insight","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Dental and Craniofacial Research; National Institute of Allergy and Infectious Diseases; Deutsche Forschungsgemeinschaft; York University; New York University Abu Dhabi","keywords":"Ameloblast; Cell biology; Enamel paint; Chemistry; ORAI1; Calbindin; STIM1; Endocrinology; Biology; Internal medicine; Calcium; Endoplasmic reticulum; Medicine; Dentistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008496571,0.000153689,0.000151621,0.00002681879,0.0003362194,0.00007482834,0.0001402594,0.000188088,0.00005947113],"category_scores_gemma":[0.00004097176,0.0001276075,0.00003491924,0.00001416129,0.0001026291,0.000005895177,0.0001414439,0.00008713258,0.00003320134],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001411109,"about_ca_system_score_gemma":0.0000842638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002818146,"about_ca_topic_score_gemma":0.0001170976,"domain_scores_codex":[0.9991997,0.00003536352,0.0001585439,0.000337557,0.00005859197,0.0002101969],"domain_scores_gemma":[0.999357,0.000007366315,0.0001024935,0.0003773336,0.00007052894,0.00008529933],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002220896,0.00007910147,0.01229131,0.00001303687,0.00006113421,0.000006308747,0.0001030853,0.000002152418,0.974084,0.000109804,0.002286103,0.01074194],"study_design_scores_gemma":[0.001676634,0.000360224,0.1078771,0.000009915067,0.00001880281,0.000007747861,0.00005024903,0.00003046023,0.2064393,0.00001914624,0.6832498,0.0002605613],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887301,0.0009929746,0.0003298756,0.0001686151,0.0003135027,0.0001477879,0.000007436061,0.00001228994,0.009297366],"genre_scores_gemma":[0.994169,0.0001939392,0.0001731331,0.0004580927,0.0002429112,0.00002114041,0.00008727118,0.00001418333,0.004640334],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7676446,"threshold_uncertainty_score":0.5203685,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008958699687272186,"score_gpt":0.2168575878924131,"score_spread":0.2078988882051409,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}