{"id":"W2602628627","doi":"10.1200/jco.2014.32.15_suppl.e22078","title":"Whole-genome DNA and RNA sequencing in patients with metastatic colorectal cancer (mCRC).","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"KRAS; Colorectal cancer; Medicine; Bevacizumab; Cancer research; Wnt signaling pathway; Cancer; Internal medicine; Gene; Biology; Genetics; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001907815,0.0002378434,0.0003029901,0.0006261139,0.0002570883,0.0003257742,0.00014079,0.0004305618,0.001428512],"category_scores_gemma":[0.0004785746,0.000126157,0.0001717621,0.0005171647,0.0001028547,0.0001104411,0.0002366763,0.0001697281,0.0003809958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001851655,"about_ca_system_score_gemma":0.000153691,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001299903,"about_ca_topic_score_gemma":0.002461488,"domain_scores_codex":[0.9998885,0.00001872278,0.00001107778,0.0000371469,0.00002647877,0.000017998],"domain_scores_gemma":[0.9998897,0.00003244124,0.00002295226,0.00000652823,0.00002256558,0.0000257895],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004894809,0.0002425685,0.5837045,0.0008046793,0.0001656804,0.02291467,0.0007331959,0.0009502441,0.2808784,0.0002069495,0.005713619,0.09879082],"study_design_scores_gemma":[0.0001874363,0.001586563,0.9200681,0.00006282725,0.0001921178,0.03307848,0.0005362964,0.002237749,0.02455362,0.0002417029,0.01723779,0.00001733055],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915387,0.002565163,0.001109056,0.0002437407,0.00001438744,0.0001071892,0.002671975,0.00006451879,0.00168521],"genre_scores_gemma":[0.9901377,0.001098107,0.00302479,0.0003194131,0.00002341261,0.00007900315,0.004128943,0.0000253556,0.001163225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001428512,"threshold_uncertainty_score":0.004778862,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03327996976372909,"score_gpt":0.3562276916923835,"score_spread":0.3229477219286544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}