{"id":"W2603510719","doi":"10.1182/blood.v128.22.4362.4362","title":"High Cumulative Illness Rating Scale (CIRS) Score in CLL Correlates with Short CLL Telomere Length and Decreased Survival","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; CancerCare Manitoba; Research Institute in Oncology and Hematology; University of Manitoba","funders":"","keywords":"Chronic lymphocytic leukemia; Internal medicine; Medicine; Telomere; Buccal swab; Gastroenterology; Cancer; Surrogate endpoint; Oncology; Leukemia; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004301849,0.0002454306,0.0004772721,0.0001532169,0.00009340097,0.00002659501,0.0001205019,0.000150704,0.0000898482],"category_scores_gemma":[0.0003576094,0.0001493028,0.00004212406,0.0003264972,0.0003101329,0.000159126,0.0001121189,0.000245752,0.00002390407],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001174992,"about_ca_system_score_gemma":0.001920999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001116514,"about_ca_topic_score_gemma":0.0009223782,"domain_scores_codex":[0.9979805,0.0001055482,0.0003253302,0.000511331,0.000545533,0.0005317425],"domain_scores_gemma":[0.9984756,0.0006409388,0.0000608149,0.000388826,0.0001474143,0.0002864446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001871144,0.001411869,0.9617326,0.0004572123,0.0004691279,0.001182091,0.001828574,0.00002494083,0.01247584,0.0005770188,0.00009594561,0.0178737],"study_design_scores_gemma":[0.3063504,0.002688607,0.4930256,0.007156154,0.001151254,0.001821473,0.003675788,0.004953732,0.176207,0.0006944679,0.000347873,0.001927607],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972758,0.000261603,0.00007475603,0.0001890207,0.00006693679,0.0006327074,0.00001609432,0.0000667213,0.001416383],"genre_scores_gemma":[0.9985583,0.0001078694,0.0005847128,0.00003965707,0.0001444767,0.00004809868,0.00001629812,0.00005296886,0.0004476426],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4687069,"threshold_uncertainty_score":0.608839,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01817511774152435,"score_gpt":0.2705986682779614,"score_spread":0.252423550536437,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}