{"id":"W2603511150","doi":"10.1101/gr.213983.116","title":"Combinatorial DNA methylation codes at repetitive elements","year":2017,"lang":"en","type":"article","venue":"Genome Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institut National Du Cancer; Ligue Contre le Cancer; Université de Strasbourg; Alliance Nationale pour les Sciences de la Vie et de la Santé; Agence Nationale de la Recherche; Centre National de la Recherche Scientifique; CNIB; Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale; Ministry of Higher Education and Scientific Research","keywords":"Biology; DNA methylation; Epigenetics; Transposable element; Genetics; Genome; Repeated sequence; DNA; Epigenomics; RNA-Directed DNA Methylation; Retrotransposon; Methylation; Interspersed repeat; 5-Methylcytosine; Human genome; Gene; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001174088,0.0001734692,0.0001962053,0.0004452124,0.0001448455,0.0001808206,0.0002108501,0.0001999191,0.000945846],"category_scores_gemma":[0.0002081814,0.0001317301,0.0002149701,0.0003052028,0.0001870485,0.0001458944,0.0001946538,0.0002564535,0.0002644952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001760488,"about_ca_system_score_gemma":0.0001228383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006379818,"about_ca_topic_score_gemma":0.001209192,"domain_scores_codex":[0.9998631,0.00001463078,0.000006017054,0.00005966732,0.0000308138,0.00002571085],"domain_scores_gemma":[0.9998177,0.00003208526,0.00006778161,0.00002826941,0.00002461611,0.0000295515],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00005837103,0.0000022247,0.002745087,0.00002656286,0.00001355251,0.00006209832,0.00002093107,0.00003936289,0.9938713,0.0001425228,0.00001126406,0.003006707],"study_design_scores_gemma":[0.00001263896,0.000271754,0.1382425,0.00001481848,0.00009837635,0.001611059,0.00006434136,0.001217001,0.8540764,0.0008418416,0.003531845,0.00001754972],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877248,0.002237906,0.008065322,0.00003581736,0.000009241753,0.00001226591,0.0004408853,0.0001029562,0.00137075],"genre_scores_gemma":[0.9953066,0.0003749761,0.002834723,0.00002328199,0.000007885224,0.000007019032,0.0004251099,0.00001422098,0.001006278],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000945846,"threshold_uncertainty_score":0.003164113,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06940763368328212,"score_gpt":0.400592951207161,"score_spread":0.3311853175238789,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}