{"id":"W2603706455","doi":"10.2196/resprot.7201","title":"Protocol for Combined Analysis of FOXFIRE, SIRFLOX, and FOXFIRE-Global Randomized Phase III Trials of Chemotherapy +/- Selective Internal Radiation Therapy as First-Line Treatment for Patients With Metastatic Colorectal Cancer","year":2017,"lang":"en","type":"article","venue":"JMIR Research Protocols","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cancer Research UK","keywords":"Selective internal radiation therapy; Medicine; Folinic acid; Oxaliplatin; Colorectal cancer; Oncology; Randomized controlled trial; Internal medicine; Radiation therapy; Clinical trial; Cancer; Hepatocellular carcinoma","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002792067,0.0003382511,0.002465782,0.0003544901,0.0003176979,0.00008848536,0.000194418,0.0001102686,0.0001124427],"category_scores_gemma":[0.0008828652,0.0002012319,0.0007223202,0.0003986395,0.0003967611,0.0001631383,0.00003098777,0.00009945632,2.879534e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000326657,"about_ca_system_score_gemma":0.0005411632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006764763,"about_ca_topic_score_gemma":0.0001481625,"domain_scores_codex":[0.9967208,0.000676623,0.001027115,0.0004903424,0.0006588986,0.0004262094],"domain_scores_gemma":[0.9952548,0.001590403,0.001214009,0.0004162362,0.001327956,0.0001965838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6793249,0.005767713,0.2409502,0.0004962385,0.009003695,0.000002808946,0.0004861347,0.000001348268,0.0003382451,0.00005395184,0.0001050853,0.06346975],"study_design_scores_gemma":[0.8599105,0.05421022,0.01895526,0.0007034911,0.001047355,6.185675e-7,0.0000159775,0.00609925,0.05635429,0.0003661195,0.00214618,0.0001907034],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.3088368,0.000008537013,0.0002533672,0.0001927364,0.000003183711,0.690262,0.0003862516,0.00001186635,0.00004529794],"genre_scores_gemma":[0.3494051,0.000009050732,0.0004309976,0.000008426262,0.00003598835,0.6498864,0.0001283924,0.00002424944,0.00007146464],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.2219949,"threshold_uncertainty_score":0.8206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3003759297275916,"score_gpt":0.5535567244901957,"score_spread":0.253180794762604,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}