{"id":"W2603706455","doi":"10.2196/resprot.7201","title":"Protocol for Combined Analysis of FOXFIRE, SIRFLOX, and FOXFIRE-Global Randomized Phase III Trials of Chemotherapy +/- Selective Internal Radiation Therapy as First-Line Treatment for Patients With Metastatic Colorectal Cancer","year":2017,"lang":"en","type":"article","venue":"JMIR Research Protocols","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cancer Research UK","keywords":"Selective internal radiation therapy; Medicine; Folinic acid; Oxaliplatin; Colorectal cancer; Oncology; Randomized controlled trial; Internal medicine; Radiation therapy; Clinical trial; Cancer; Hepatocellular carcinoma","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.06323114,0.005683791,0.0079881,0.003059016,0.00389064,0.005317902,0.004618827,0.006406668,0.09705489],"category_scores_gemma":[0.07699119,0.003337511,0.006317066,0.004649274,0.003395551,0.002828352,0.003327029,0.01293993,0.02153858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.008439504,"about_ca_system_score_gemma":0.02380034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00202794,"about_ca_topic_score_gemma":0.0055539,"domain_scores_codex":[0.9329518,0.04904109,0.005476583,0.004925991,0.004713145,0.002891367],"domain_scores_gemma":[0.9544928,0.01143781,0.006145261,0.01094518,0.01205996,0.004918863],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.6404245,0.00684847,0.001924947,0.02615518,0.005994624,0.000654984,0.0007250011,0.003789527,0.006127742,0.01991328,0.2066312,0.08081046],"study_design_scores_gemma":[0.6030363,0.01405412,0.004620254,0.006466168,0.001672232,0.000184347,0.0001811211,0.003853532,0.002187759,0.006635149,0.3569036,0.0002053408],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.0006673117,0.0002248159,0.003846304,0.0004075345,0.0009878544,0.9860852,0.004331671,0.0002433089,0.00320594],"genre_scores_gemma":[0.0009103943,0.00007302459,0.003822543,0.000325525,0.00009918166,0.9929327,0.000783377,0.00002648132,0.001026782],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.09705489,"threshold_uncertainty_score":0.3344022,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3003759297275916,"score_gpt":0.5535567244901957,"score_spread":0.253180794762604,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}