{"id":"W2604145475","doi":"10.1038/cdd.2017.21","title":"Transglutaminases factor XIII-A and TG2 regulate resorption, adipogenesis and plasma fibronectin homeostasis in bone and bone marrow","year":2017,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Blood properties and coagulation","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"Shriners Hospitals for Children - Canada; McGill University","funders":"Institute of Musculoskeletal Health and Arthritis; Canadian Institutes of Health Research; Università degli Studi di Pavia; China Scholarship Council; Institute of Genetics; Réseau de Recherche en Santé Buccodentaire et Osseuse; McGill University","keywords":"RANKL; Adipogenesis; Osteoclast; Osteoprotegerin; Bone resorption; Chemistry; Endocrinology; Internal medicine; Cell biology; Bone marrow; Bone remodeling; Mesenchymal stem cell; Osteoblast; Biology; Receptor; Biochemistry; Medicine; In vitro; Activator (genetics)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000249398,0.0002390337,0.0001978185,0.000385318,0.0001833286,0.0006903793,0.0002075039,0.0002555755,0.0009391624],"category_scores_gemma":[0.0001991119,0.0001671734,0.000187682,0.0001896644,0.0003517267,0.0002897136,0.0003635558,0.0005458049,0.0002624642],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003807569,"about_ca_system_score_gemma":0.0002443949,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001016082,"about_ca_topic_score_gemma":0.001150864,"domain_scores_codex":[0.9998465,0.00004178155,0.0000106316,0.00002464844,0.00003306495,0.0000434517],"domain_scores_gemma":[0.9999094,0.00001208653,0.00002604343,0.000008525815,0.0000123988,0.00003163353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001022381,0.00001518951,0.00162049,0.0000288693,0.00001414555,0.0001502702,0.00005619045,0.00005898376,0.9919724,0.000795875,0.0001073905,0.004157702],"study_design_scores_gemma":[0.0001944834,0.0006366068,0.06662633,0.00001862359,0.0001036978,0.001652359,0.0003604084,0.001607671,0.9174919,0.001287063,0.01000512,0.0000158183],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9812165,0.01196055,0.004025299,0.0001919156,0.00003324625,0.00001878861,0.0001825479,0.00006120598,0.002309975],"genre_scores_gemma":[0.9928353,0.001699116,0.001345872,0.00004532566,0.0000186729,0.00001458837,0.0002540706,0.00002077372,0.00376622],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001016082,"threshold_uncertainty_score":0.00314182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02220900366474482,"score_gpt":0.2315999173752436,"score_spread":0.2093909137104988,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}